ArticleAIDS care2019
High prevalence of non-adherence to antiretroviral therapy among undisclosed HIV-infected children in Ghana.
Article in AIDS care, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Factors Influencing Adherence to Pediatric Antiretroviral Therapy: Experience from a Tertiary Care Center in Oman.Cureus · 2026Article
- Perceived satisfaction with HIV care and its impact on medication adherence and clinical outcomes: a cross-sectional study in Kumasi, Ghana.BMC infectious diseases · 2026Article
- Understanding Antiretroviral Therapy Adherence in Children With HIV: A Review of Barriers and Strategies.AIDS research and treatment · 2026Review
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- The association of HIV-related stigma and psychosocial factors and HIV treatment outcomes among people living with HIV in the Volta region of Ghana: A mixed-methods study.PLOS global public health · 2024Article
- Predictors of HIV status disclosure among people living with HIV (PLHIV) in Ghana: the disclosure conundrum and its policy implications in resource limited settings.AIDS research and therapy · 2023Article
- A phenomenological study of the beliefs of family caregivers of children living with HIV/AIDS on adherence to antiretroviral therapy.Nursing open · 2023Article
- The predictors of unsuppressed viremia among PLHIV: a cross-sectional study in Ghana.BMC public health · 2023Article
- Adherence to antiretroviral therapy among HIV patients in Ghana: A systematic review and meta-analysis.PLOS global public health · 2023Article
- Factors influencing adherence to antiretroviral therapy among HIV/AIDS patients in the Ga West Municipality, Ghana.IJID regions · 2022Article
- Predictors and consequences of HIV status disclosure to adolescents living with HIV in Eastern Cape, South Africa: a prospective cohort study.Journal of the International AIDS Society · 2022Article
- Illness perceptions, social support and antiretroviral medication adherence in people living with HIV in the greater Accra region, Ghana.Nursing open · 2021Article
- HIV virological non-suppression and its associated factors in children on antiretroviral therapy at a major treatment centre in Southern Ghana: a cross-sectional study.BMC infectious diseases · 2021Article
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Authors and funding
12 authors.
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Abstract
Adherence to antiretroviral therapy (ART) remains one of the greatest obstacles in pediatric HIV care. We sought to determine the prevalence of adherence to ART among undisclosed HIV-infected children and adolescents in Ghana. We analyzed baseline data from HIV-infected children and adolescents aged 7-18 years old enrolled in the SANKOFA Pediatric HIV disclosure intervention study in Ghana. Antiretroviral medication adherence was measured using caregiver 3-day recall; child 3-day recall; and pharmacy records for antiretroviral time-to-refill. Four hundred and twenty child-caregiver dyads were enrolled from January 2013 to June 2016. The median adherence (interquartile range), as measured by time-to-refill, was 93.2% (68.0%-100.0%). However, only 47.5% of children had ≥95% adherence ("good adherence") using time-to-refill data. Children of caregivers who had received secondary or higher level of education versus no school (aOR, 2.90, 95% Confidence Interval, CI 1.29-6.56), p = 0.010) or elementary education only (aOR, 2.20, CI, 1.24-3.88, p = 0.007) were more likely to have "good adherence" (≥95%). In this cohort of children unaware of their HIV positive status, median ART adherence rate was sub-optimal (by World Health Organization definition) while 38% had poor adherence (<85%).
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