Evidence map›Paper›PMID 30235840›Full record

ReviewViruses2018

HSV-Induced Systemic Inflammation as an Animal Model for Behçet's Disease and Therapeutic Applications.

S M Shamsul Islam, Seonghyang Sohn

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Frontiers in immunology · 2021
    Article
  6. Article
  7. Article
  8. Article
  9. Behçet's disease: A (silk) route to atrial fibrillation?International journal of cardiology · 2019
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

S M Shamsul IslamDepartment of Biomedical Science, Ajou University School of Medicine, Suwon 16499, Korea. shamsulislam21@gmail.com.ORCID 0000-0003-0617-1698
Seonghyang SohnDepartment of Biomedical Science, Ajou University School of Medicine, Suwon 16499, Korea. sohnsh@ajou.ac.kr.
Ajou University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Behçet's disease (BD) affects multiple organs. It is mainly characterized by recurrent oral, skin, and genital aphthous ulcers, and eye involvement. Successful management of BD is increasing, although its etiology remains unclear. A number of etiologies have been proposed, including environmental, genetic, viral, and immunological factors. To understand its complex etiology and improve its management, animal models of BD have been used to enable more effective therapeutic applications with increased clinical significance. An herpes simplex virus (HSV) type 1-induced BD mouse model has shown disease characteristics similar to those seen in BD patients. An HSV-induced BD animal model has been used to test various therapeutic modalities. The applied modalities are several materials that are derived from natural products, conventional therapeutics, and possible biologics. In this review, we provided how they regulate inflammation in an HSV-induced BD model.

Indexed as

SimplexvirusAnimalsBehcet SyndromeCombined Modality TherapyDisease Models, AnimalDisease SusceptibilityGenetic Predisposition to DiseaseHerpes SimplexHumansMiceanimal modelapplicationBehçet’s diseaseherpes simplex virus

Identifiers

PMID30235840
PMCPMC6163530
OpenAlexW2890356109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.