Evidence map›Paper›PMID 30235825›Full record

ArticleNutrients2018

Weizhe Zhang, Jingang Hou, Xiaotong Yan, Jing Leng, Rongyan Li, Jing Zhang, Jingjing Xing, Chen Chen, Zi Wang, Wei Li

Abstract read
In one paragraph

Article in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Pro-Inflammatory Signalling PRRopels Cisplatin-Induced Toxicity.International journal of molecular sciences · 2022
    Review
  12. Article
  13. Crude Saponin fromAntioxidants (Basel, Switzerland) · 2021
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Weizhe ZhangDepartment of Chinese Materia Medica, College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China. WeizheZhang1215@163.com.
Jingang HouDepartment of Chinese Materia Medica, College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China. houjg2014@kaist.ac.kr.ORCID 0000-0003-2194-0870
Xiaotong YanDepartment of Chinese Materia Medica, College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China. yanxiaotong0707@126.com.
Jing LengDepartment of Chinese Materia Medica, College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China. lj170907@126.com.
Rongyan LiDepartment of Chinese Materia Medica, College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China. lyr19930612@126.com.
Jing ZhangDepartment of Chinese Materia Medica, College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China. zhjing0701@163.com.
Jingjing XingDepartment of Chinese Materia Medica, College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China. m13944152775_3@163.com.
Chen ChenSchool of Biomedical Sciences, University of Queensland, Brisbane 4072, Australia. chen.chen@uq.edu.au.ORCID 0000-0003-2104-534X
Zi WangDepartment of Chinese Materia Medica, College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China. wangzi8020@126.com.
Wei LiDepartment of Chinese Materia Medica, College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China. liwei7727@126.com.ORCID 0000-0002-2988-4298

Funding

Jilin Science & Technology Development Plan 20180201083YY
6 · The paper itself

Abstract

Although cisplatin is a potent chemotherapeutic agent against cancers, its clinical application is seriously limited by its severe side effects of nephrotoxicity. Previous studies reported that saponins isolated from the roots of

Indexed as

CisplatinPlatycodonAcute Kidney InjuryAnimalsAnti-Inflammatory AgentsApoptosisCytoprotectionDisease Models, AnimalInflammation MediatorsKidneyMaleMice, Inbred ICRNF-kappa BPhosphatidylinositol 3-KinaseProto-Oncogene Proteins c-aktSaponinsAnti-Inflammatory AgentsCisplatinInflammation MediatorsNF-kappa BPhosphatidylinositol 3-KinaseProto-Oncogene Proteins c-aktSaponinscisplatininflammationnephrotoxicityNF-κBPI3K/Akt/ApoptosisPlatycodon grandiflorum saponins

Identifiers

PMID30235825
PMCPMC6164643

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.