Evidence map›Paper›PMID 30234441›Full record

ArticleTissue engineering. Part A2019

Effect of Electron Beam Sterilization on Three-Dimensional-Printed Polycaprolactone/Beta-Tricalcium Phosphate Scaffolds for Bone Tissue Engineering.

Arnaud Bruyas, Seyedsina Moeinzadeh, Sungwoo Kim, David W Lowenberg, Yunzhi Peter Yang

Open access · greenAbstract read
In one paragraph

Article in Tissue engineering. Part A, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
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  5. 3D Hybrid Bioprinting for Complex Multi-Tissue Engineering.bioRxiv : the preprint server for biology · 2025
    Article
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  20. Development of PLGA-PEG-COOH and gelatin-based microparticles dual delivery system and E-beam sterilization effects for controlled release of BMP-2 and IGF-1.Particle & particle systems characterization : measurement and description of particle properties and behavior in powders and other disperse systems · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Arnaud Bruyas1 Department of Orthopaedic Surgery and of Bioengineering and of Material Science and Engineering, Stanford University, Stanford, California.
Seyedsina Moeinzadeh1 Department of Orthopaedic Surgery and of Bioengineering and of Material Science and Engineering, Stanford University, Stanford, California.
Sungwoo Kim1 Department of Orthopaedic Surgery and of Bioengineering and of Material Science and Engineering, Stanford University, Stanford, California.
David W Lowenberg1 Department of Orthopaedic Surgery and of Bioengineering and of Material Science and Engineering, Stanford University, Stanford, California.
Yunzhi Peter Yang2 Department of Orthopaedic Surgery, of Bioengineering and of Material Science and Engineering, Stanford University, Stanford, California.
Stanford Medicine · USStanford University · US

Funding

Microengineered Osteons for Bone Tissue EngineeringR01AR057837 · NIAMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI YANG, YUNZHI · 2010 to 2018
$5.1M
Systems Modeling Guided Bone regenerationU01AR069395 · NIAMS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI YANG, YUNZHI, ZHOU, XIAOBO · 2016 to 2021
$3.4M
NIAMS NIH HHS R01 AR057837NIAMS NIH HHS U01 AR069395
6 · The paper itself

Abstract

impact statementProviding customized geometries and improved control in physical and biological properties, 3D-printed polycaprolactone/beta-tricalcium phosphate (PCL/β-TCP) composite constructs are of high interest for bone tissue engineering applications. A critical step toward the translation and clinical applications of these types of scaffolds is terminal sterilization, and E-beam irradiation might be the most relevant method because of PCL properties. Through in vitro experimental testing of both physical and biological properties, it is proven in this article that E-beam irradiation is relevant for sterilization of 3D-printed PCL/β-TCP scaffolds for bone tissue engineering applications.

Indexed as

ElectronsPrinting, Three-DimensionalAnimalsBone and BonesCalcium PhosphatesCell LineMicePolyestersSterilizationTissue EngineeringTissue Scaffoldsbeta-tricalcium phosphateCalcium PhosphatespolycaprolactonePolyesters3D printingbone tissue engineeringcompositeelectron beam sterilizationPCL

Identifiers

PMID30234441
PMCPMC6388713
OpenAlexW2889585934

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.