ArticleDevelopmental psychology2018
Discrimination, segregation, and chronic inflammation: Testing the weathering explanation for the poor health of Black Americans.
Article in Developmental psychology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
106 citing papers in PubMed, 1 synthesis or guideline pooled it, 178 citations in OpenAlex.
- The Association between Maternal Experiences of Interpersonal Discrimination and Adverse Birth Outcomes: A Systematic Review of the Evidence.International journal of environmental research and public health · 2021Pooled it
- Mood reactivity to daily social conflict in hostile adults: An experimental intervention.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2025Trial
- Racism and alterations in brain structure and function: A narrative review of emerging neuroimaging evidence in racialized individuals.Cognitive, affective & behavioral neuroscience · 2026Review
- Adverse policing as a social exposome pathway: Implications for depression, cognition, and dementia risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Neighborhood Deprivation, Trauma Profiles, Coping, and Stress Prospectively Predict Depressive Symptoms Among Young African American Mothers in the InterGEN Study: A Latent Class Analysis.Journal of racial and ethnic health disparities · 2026Article
- Epigenetic entropy, socioeconomic differences, and health and lifespan in the Women's Health Initiative.Clinical epigenetics · 2026Article
- Reparations for Indigenous Peoples in the USA and Canada.PLOS global public health · 2026Article
- Intersecting social determinants of health, multimorbidity and quality of life in people of Black ethnicities with HIV in South London.AIDS (London, England) · 2025Article
- A population health analysis of trends in lower extremity amputation secondary to diabetes and peripheral artery disease, 2016-2023.Diabetes research and clinical practice · 2025Observational
- A latent measure of cultural racism and its association with US mortality and life expectancy.Nature human behaviour · 2025Article
- Weathering the STORM and Forecasting Equity for Older Black Women: Expanding Social Determinants of Health.International journal of environmental research and public health · 2025Article
- Non-inclusive language in human subjects questionnaires: addressing racial, ethnic, heteronormative, and gender bias.BMC public health · 2025Article
- Post-Heroin Post-Traumatic Stress Disorder Spectrum: Heroin Addiction as a Generator of Trauma Sensitisation in Everyday Life: A Perspective Review.Journal of clinical medicine · 2025Article
- Racial/Ethnic Residential Clustering, Experiences with Discrimination, and Self-Rated Health across the Houston Area.Journal of racial and ethnic health disparities · 2025Article
- Determinants of Suicidal Ideation Among Immigrant Women With Cumulative Exposures to Violence: The Role of Resilience and Social Support.Journal of aggression, maltreatment & trauma · 2025Article
- Disparities in the association of ambient air pollution with childhood asthma incidence in the ECHO consortium: A US-wide multi-cohort study.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Self-Advocacy Among Black Women During the Perinatal Period: Prevalence and Relationship to Patient Experiences.Birth (Berkeley, Calif.) · 2025Article
- Association of Historical Redlining With Gestational Diabetes Mellitus: The Mediating Role of BMI and Area Deprivation Index.Diabetes care · 2025Article
- Healthcare inequities and healthcare providers: we are part of the problem.International journal for equity in health · 2025Review
- Perceived Experiences of racism in Relation to Genome-Wide DNA Methylation and Epigenetic Aging in the Black Women's Health Study.Journal of racial and ethnic health disparities · 2025Article
46 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
Several studies have reported a relation between race-related stressors and the poor health of Black Americans. Such findings raise questions regarding the mediating biological mechanisms that might account for this link. The present study investigated elevated systemic inflammation, a factor shown to be a strong predictor of chronic illness and mortality in all ethnic populations, as a possible factor. Using 7 waves of data from the Family and Community Health Study, collected over a 20-year period from over 400 Black Americans, we investigated the extent to which exposure to discrimination and segregation at various points in the life course predicted adult inflammation at age 28. Our analyses examined whether cumulative stress, stress generation, or predictive adaptive response (PAR) models best accounted for any associations that existed between these race-related stressors and adult inflammation. At every wave of data collection, assessments of discrimination and segregation were related to adult inflammation. However, multivariate analyses using structure equation modeling indicated that the PAR model best explained the effect of these race-related stressors on inflammation. Exposure to discrimination and segregation during the juvenile years predicted adult inflammation and amplified the inflammatory effect of adult exposure to these race-related stressors. These effects were considerably more robust than that of traditional health risk factors such as diet, exercise, smoking, and low SES. Implications of these findings are discussed, including the limitations of the widely accepted risk factor approach to increasing the health of Black Americans. (PsycINFO Database Record
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.