Evidence map›Paper›PMID 30234098›Full record

ArticleFrontiers in chemistry2018

Design, Synthesis and Biological Activity Evaluation of S-Substituted 1

Marius Mioc, Sorin Avram, Vasile Bercean, Ludovic Kurunczi, Roxana M Ghiulai, Camelia Oprean, Dorina E Coricovac, Cristina Dehelean, Alexandra Mioc, Mihaela Balan-Porcarasu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 30 citations in OpenAlex.

  1. In Vitro and In Silico Evaluation ofPlants (Basel, Switzerland) · 2024
    Article
  2. A Pharmacological Update of Triazole Derivative: A Review.Current topics in medicinal chemistry · 2024
    Review
  3. Review
  4. Antiviral Effect of Polyphenolic Substances inEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Marius MiocFaculty of Pharmacy, 'Victor Babes' University of Medicine and Pharmacy, Timisoara, Romania.
Sorin AvramDepartment of Computational Chemistry, Institute of Chemistry Timisoara of the Romanian Academy, Timisoara, Romania.
Vasile BerceanS.C. SINOFIN S.R.L., Timisoara, Romania.
Ludovic KuruncziDepartment of Computational Chemistry, Institute of Chemistry Timisoara of the Romanian Academy, Timisoara, Romania.
Roxana M GhiulaiFaculty of Pharmacy, 'Victor Babes' University of Medicine and Pharmacy, Timisoara, Romania.
Camelia OpreanFaculty of Pharmacy, 'Victor Babes' University of Medicine and Pharmacy, Timisoara, Romania.
Dorina E CoricovacFaculty of Pharmacy, 'Victor Babes' University of Medicine and Pharmacy, Timisoara, Romania.
Cristina DeheleanFaculty of Pharmacy, 'Victor Babes' University of Medicine and Pharmacy, Timisoara, Romania.
Alexandra MiocFaculty of Pharmacy, 'Victor Babes' University of Medicine and Pharmacy, Timisoara, Romania.
Mihaela Balan-PorcarasuInstitute of Macromolecular Chemistry 'Petru Poni ', Iasi, Romania.
Calin Tatu"Pius Brinzeu" Timisoara County Emergency Clinical Hospital, Oncogen Institute, Timisoara, Romania.
Codruta SoicaFaculty of Pharmacy, 'Victor Babes' University of Medicine and Pharmacy, Timisoara, Romania.
Victor Babeș University of Medicine and Pharmacy Timișoara · RORomanian Academy · ROSpitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colon cancer is a widespread pathology with complex biochemical etiology based on a significant number of intracellular signaling pathways that play important roles in carcinogenesis, tumor proliferation and metastasis. These pathways function due to the action of key enzymes that can be used as targets for new anticancer drug development. Herein we report the synthesis and biological antiproliferative evaluation of a series of novel S-substituted 1

Indexed as

124-triazoleantiproliferativecell cyclecolon cancerdocking

Identifiers

PMID30234098
PMCPMC6134806
OpenAlexW2891232912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.