ReviewFrontiers in public health2018
Emergence of Monkeypox as the Most Important Orthopoxvirus Infection in Humans.
Review in Frontiers in public health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 294 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
294 citing papers in PubMed, 7 syntheses or guidelines pooled it, 648 citations in OpenAlex.
- Knowledge and attitude toward monkeypox (mpox) among healthcare providers in Sub-Saharan Africa: a systematic review and meta-analysis.Systematic reviews · 2026Pooled it
- Mpox knowledge and positive attitudes in Sub-Saharan African healthcare workers after 2022 outbreak of disease: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2026Pooled it
- Global epidemiology, viral evolution, and public health responses: a systematic review on Mpox (1958-2024).Journal of global health · 2025Pooled it
- Global knowledge and attitudes towards mpox (monkeypox) among healthcare workers: a systematic review and meta-analysis.International health · 2024Pooled it
- A global systematic evidence review with meta-analysis of the epidemiological characteristics of the 2022 Mpox outbreaks.Infection · 2024Pooled it
- Integrated Network Analysis of Symptom Clusters Across Monkeypox Epidemics From 1970 to 2023: Systematic Review and Meta-Analysis.JMIR public health and surveillance · 2024Pooled it
- Clinical Features, Antiviral Treatment, and Patient Outcomes: A Systematic Review and Comparative Analysis of the Previous and the 2022 Mpox Outbreaks.The Journal of infectious diseases · 2023Pooled it
- An open-label, non-randomized study investigating the safety and efficacy of smallpox vaccine, LC16, as post-exposure prophylaxis for mpox.Human vaccines & immunotherapeutics · 2023Trial
- A comprehensive overview of monkeypox virus disease.Tropical medicine and health · 2026Review
- From behavioral to structural correlates: a multi-phase analysis of global reported mpox.BMC medicine · 2026Article
- Mapping Mpox vaccine hesitancy using an integrated machine learning and structural equation modeling approach.Scientific reports · 2026Article
- Epidemiological, clinical and virological profile of Mpox in Kinshasa, democratic republic of the Congo, 2024-2025: a cross-sectional study.BMC infectious diseases · 2026Article
- Article
- A dynamically consistent discrete-time model for monkeypox transmission with implications for quarantine policies.BMC public health · 2026Article
- Review
- Monkeypox (Mpox), a Resurging Global Public Health Concern: An Updated Outlook Through 2025.Current issues in molecular biology · 2026Review
- Advanced strategies for the diagnosis, treatment, and vaccination of monkeypox.Journal of nanobiotechnology · 2026Review
- Community awareness and attitude in Al-Jouf region toward monkeypox.Journal of family medicine and primary care · 2026Article
- Human Monkeypox knowledge gaps among nurses: implications for training and outbreak preparedness.BMC medical education · 2026Article
- The emergence of Clade IIb and Ib mpox viruses: a state-of-the-art review.Annals of medicine and surgery (2012) · 2026Review
234 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Monkeypox is an emerging zoonotic disease recognized as the most important orthopoxvirus infection in humans in the smallpox post-eradication era. The clinical presentation of monkeypox is similar to the one of smallpox. The case fatality rate of monkeypox (10%) lies between the case fatality rate of variola major (30%) and variola minor (1%). The disease is endemic in the Democratic Republic of the Congo, but other countries of Central and West Africa either reported cases of monkeypox in humans or circulation in wildlife. The disease was also imported once into the USA. The disease has always been considered rare and self-limiting, however recent sporadic reports suggest otherwise. Unfortunately, the collected data is limited, dispersed and often incomplete. Therefore, the objective of this review is to trace all reported human monkeypox outbreaks and relevant epidemiological information. The frequency and geographical spread of human monkeypox cases have increased in recent years, and there are huge gaps in our understanding of the disease's emergence, epidemiology, and ecology. The monkeypox virus is considered a high threat pathogen causing a disease of public health importance. Therefore, there is an urgent need to focus on building surveillance capacities which will provide valuable information for designing appropriate prevention, preparedness and response activities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.