Evidence map›Paper›PMID 30233874›Full record

ArticleJournal of thoracic disease2018

Discrepancies between ALK protein disruption and occurrence of

Anna Grenda, Bożena Jarosz, Paweł Krawczyk, Tomasz Kucharczyk, Kamila Wojas-Krawczyk, Katarzyna Reszka, Kinga Krukowska, Marcin Nicoś, Juliusz Pankowski, Maciej Bryl and 9 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of thoracic disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Anna GrendaDepartment of Pneumonology, Oncology and Allergology, Medical University of Lublin, Lublin, Poland.
Bożena JaroszDepartment of Neurosurgery and Pediatric Neurosurgery, Medical University of Lublin, Lublin, Poland.
Paweł KrawczykDepartment of Pneumonology, Oncology and Allergology, Medical University of Lublin, Lublin, Poland.
Tomasz KucharczykDepartment of Pneumonology, Oncology and Allergology, Medical University of Lublin, Lublin, Poland.
Kamila Wojas-KrawczykDepartment of Pneumonology, Oncology and Allergology, Medical University of Lublin, Lublin, Poland.
Katarzyna ReszkaGenetics and Immunology Laboratory Genim LLC, Lublin, Poland.
Kinga KrukowskaGenetics and Immunology Laboratory Genim LLC, Lublin, Poland.
Marcin NicośDepartment of Pneumonology, Oncology and Allergology, Medical University of Lublin, Lublin, Poland.
Juliusz PankowskiDepartment of Pathology, Pulmonary Hospital, Zakopane, Poland.
Maciej BrylE.J. Zeyland Greatpoland Center of Pulmonology and Thoracic Surgery, Poznan, Poland.
Rodryg RamlauDepartment of Oncology, Allergology and Respiratory Oncology, Poznan University of Medical Sciences, Poznan, Poland.
Barbara Kuźnar-KamińskaDepartment of Pulmonology, Allergology and Respiratory Oncology, Poznan University of Medical Sciences, Poznan, Poland.
Tomasz GrodzkiDepartment of Thoracic Surgery, Regional Hospital for Lung Diseases, Szczecin-Zdunowo, Poland.
Aleksandra SzczęsnaMazovian Centre for Treatment of Lung Diseases and Tuberculosis, Otwock, Poland.
Krystyna SiemiątkowskaDepartment of Pathomorphology, Kuyavian-Pomeranian Center of Pulmonology, Bydgoszcz, Poland.
Justyna SzumiłoDepartment of Pathomorphology, Medical University of Lublin, Lublin, Poland.
Halina Batura-GabryelDepartment of Pulmonology, Allergology and Respiratory Oncology, Poznan University of Medical Sciences, Poznan, Poland.
Michał PalonkaDepartment of Pneumonology, Oncology and Allergology, Medical University of Lublin, Lublin, Poland.
Janusz MilanowskiDepartment of Pneumonology, Oncology and Allergology, Medical University of Lublin, Lublin, Poland.
Medical University of Lublin · PLPoznan University of Medical Sciences · PLCentral Clinical Hospital · PLPomeranian Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNon-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (

methodsMutations in

resultsThe frequency of

conclusionsWe indicated that diagnosis of ALK disruption in NSCLC patients should be notably careful using IHC and FISH methods. Recommendations for ALK diagnosis should include the way of interpretation of cases with low percentage of cells with abnormal ALK protein expression in IHC test, character of IHC reaction, and cases with

Indexed as

ALK rearrangementdiagnostic issueEGFR mutationnon-small cell lung cancer (NSCLC)

Identifiers

PMID30233874
PMCPMC6129873
OpenAlexW2884160001

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.