Evidence map›Paper›PMID 30233866›Full record

ArticleJournal of thoracic disease2018

Application of albumin/globulin ratio in elderly patients with acute exacerbation of chronic obstructive pulmonary disease.

Jinqiu Qin, Yuanyuan Qin, Yangyang Wu, Aiqiu Wei, Meiling Luo, Lin Liao, Faquan Lin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thoracic disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Frailty in COPD: Clinical Impact, Diagnosis, Biomarkers, and Management Strategies.International journal of chronic obstructive pulmonary disease · 2025
    Pooled it
  2. Pooled it
  3. A Narrative Review of the Correlation Between Comorbidity and Acute Exacerbation of COPD Patients.International journal of chronic obstructive pulmonary disease · 2026
    Review
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  9. Protein corona and exosomes: new challenges and prospects.Cell communication and signaling : CCS · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jinqiu QinDepartment of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Yuanyuan QinDepartment of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Yangyang WuDepartment of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Aiqiu WeiDepartment of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Meiling LuoDepartment of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Lin LiaoDepartment of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.
Faquan LinDepartment of Clinical Laboratory, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute exacerbation of chronic obstructive pulmonary disease (AECOPD) has become an important disease of hospitalized elderly patients, which lack simple and inexpensive indicators for evaluating the condition and prognosis. This study was performed to investigate the clinical significance of the serum albumin/globulin ratio (AGR) in elderly patients with AECOPD.

methodsThe data of 252 hospitalized elderly patients with AECOPD, 89 stable COPD patients and 115 elderly healthy individuals were analyzed and compared. The differences in the AGR, logarithm of the serum C-reactive protein (LogCRP) level, prealbumin (PA) level, and immunoglobulin G (IgG) level were compared. AECOPD patients were grouped using the optimal cutoff values of each index to compare the difference in the combined infection rate. The correlation between hospital stays and AGR was analyzed.

resultsThe AGR, LogCRP, PA level, and IgG level were different among the AECOPD group, stable COPD group and healthy control groups (P<0.05). The AGR, LogCRP, and PA level were different (P<0.05) among the Global Initiative for Chronic Obstructive Lung Disease (GOLD) I, II, II, and IV groups. Age, AGR, LogCRP, and PA level were different (P<0.05) between the infection and non-infection groups. After grouping according to the optimal cutoff values, the combined infection rate was different (P<0.05). The AGR was negatively correlated with the hospital stay (r=-0.583, P<0.001). The hospital stay was longer in patients with an AGR of <1.37 than ≥1.37 (P<0.001).

conclusionsThe AGR can be regarded as a reference index for evaluating the condition of elderly patients with AECOPD, determining the presence of combined infection, and predicting the prognosis.

Indexed as

Acute exacerbation of chronic obstructive pulmonary disease (AECOPD)albumin/globulin ratio (AGR)combined infectionC-reactive protein (CRP)prealbumin (PA)

Identifiers

PMID30233866
PMCPMC6129906

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.