Evidence map›Paper›PMID 30233542›Full record

ArticleFrontiers in microbiology2018

Development of a Colloidal Gold-Based Immunochromatographic Strip for Rapid Detection of H7N9 Influenza Viruses.

Zhihao Sun, Baolan Shi, Feifei Meng, Ruonan Ma, Qingyun Hu, Tao Qin, Sujuan Chen, Daxin Peng, Xiufan Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

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  11. Development of an antigen-ELISA and a colloidal gold-based immunochromatographic strip based on monoclonal antibodies for detection of avian influenza A(H5) viruses.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Zhihao SunCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Baolan ShiSinopharm Yangzhou Vac Biological Engineering Co., Ltd., Yangzhou, China.
Feifei MengCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Ruonan MaCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Qingyun HuCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Tao QinCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Sujuan ChenCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Daxin PengCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Xiufan LiuCollege of Veterinary Medicine, Yangzhou University, Yangzhou, China.
Yangzhou University · CNChinese Academy of International Trade and Economic Cooperation · CNChina National Pharmaceutical Group Corporation (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both high- and low-pathogenic H7N9 influenza A virus (IAV) infections have been found in human and poultry in China, and most human cases are related to contact with infected poultry. It is necessary to develop a rapid and simple method to detect H7N9 IAV in poultry. In this study, 13 monoclonal antibodies (McAbs) against the H7N9 IAV hemagglutinin were developed, and three critical amino acid epitopes (198, 227, 235) were identified based on the reactivity of these variant and wild-type strains with the McAbs. We developed an immunochromatographic assay for H7N9 AIVs using two McAbs recognizing the epitope position 227 and 235. The assay had good specificity, stability, and sensitivity, with a detection limit of swab and tissue samples of 2.5 log

Indexed as

epitopegold immunochromatographic stripH7N9influenzamonoclonal antibody

Identifiers

PMID30233542
PMCPMC6127252
OpenAlexW2889061487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.