Evidence map›Paper›PMID 30233503›Full record

ArticleFrontiers in microbiology2018

Identification of Halophilic Microbes in Lung Fibrotic Tissue by Oligotyping.

Corina N D'Alessandro-Gabazza, Celia Méndez-García, Osamu Hataji, Sara Westergaard, Fumiaki Watanabe, Taro Yasuma, Masaaki Toda, Hajime Fujimoto, Kota Nishihama, Kentaro Fujiwara and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  5. The lung microbiome in interstitial lung disease.Breathe (Sheffield, England) · 2025
    Review
  6. Review
  7. Review
  8. The Lung Microbiome.Journal of immunology (Baltimore, Md. : 1950) · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Oral dysbiosis induced byJournal of oral microbiology · 2020
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Corina N D'Alessandro-GabazzaDepartment of Immunology, Mie University, Tsu, Japan.
Celia Méndez-GarcíaCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, United States.
Osamu HatajiRespiratory Center, Matsusaka Municipal Hospital, Matsusaka, Japan.
Sara WestergaardDepartment of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, IL, United States.
Fumiaki WatanabeRespiratory Center, Matsusaka Municipal Hospital, Matsusaka, Japan.
Taro YasumaDepartment of Immunology, Mie University, Tsu, Japan.
Masaaki TodaDepartment of Immunology, Mie University, Tsu, Japan.
Hajime FujimotoDepartment of Pulmonary and Critical Care Medicine, Mie University, Tsu, Japan.
Kota NishihamaDepartment of Diabetes and Endocrinology, Mie University, Tsu, Japan.
Kentaro FujiwaraDepartment of Pulmonary and Critical Care Medicine, Mie University, Tsu, Japan.
Osamu TaguchiCenter for Physical and Mental Health, Mie University, Tsu, Japan.
Tetsu KobayashiDepartment of Pulmonary and Critical Care Medicine, Mie University, Tsu, Japan.
Roderick I MackieCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, United States.
Isaac CannCarl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, United States.
Esteban C GabazzaDepartment of Immunology, Mie University, Tsu, Japan.
Mie University · JPUniversity of Illinois Urbana-Champaign · USSoka Municipal Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Idiopathic pulmonary fibrosis (IPF) is an incurable disease with poor prognosis and unknown etiology. The poor clinical outcome is associated with enhanced microbial burden in bronchoalveolar lavage fluid from IPF patients. However, whether microbes from the respiratory tract fluid cause the disease remains uncertain. Tissue-associated microbes can influence host physiology in health and disease development. The aim of this study was to evaluate the existence of microbes in lung fibrotic tissues. We evaluated the microbial community in lung tissues from IPF and from human transforming growth factor-β1 (TGF-β1) transgenic mice with lung fibrosis by oligotyping. We also evaluated the microbial population in non-tumor-bearing tissues from surgical specimens of lung cancer patients. The phyla

Indexed as

cancerepithelial cellsfibrosislung tissuemicrobesmouse model

Identifiers

PMID30233503
PMCPMC6127444
OpenAlexW2889526713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.