Evidence map›Paper›PMID 30233480›Full record

ArticleFrontiers in neurology2018

Conscious While Being Considered in an Unresponsive Wakefulness Syndrome for 20 Years.

Audrey Vanhaudenhuyse, Vanessa Charland-Verville, Aurore Thibaut, Camille Chatelle, Jean-Flory L Tshibanda, Audrey Maudoux, Marie-Elisabeth Faymonville, Steven Laureys, Olivia Gosseries

Abstract read
In one paragraph

Article in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Audrey VanhaudenhuyseDepartment of Algology and Palliative Care, University Hospital of Liege, Liege, Belgium.
Vanessa Charland-VervilleGIGA-Consciousness, Coma Science Group & Neurology Department, University Hospital of Liege, Liege, Belgium.
Aurore ThibautGIGA-Consciousness, Coma Science Group & Neurology Department, University Hospital of Liege, Liege, Belgium.
Camille ChatelleGIGA-Consciousness, Coma Science Group & Neurology Department, University Hospital of Liege, Liege, Belgium.
Jean-Flory L TshibandaGIGA-Consciousness, Coma Science Group & Neurology Department, University Hospital of Liege, Liege, Belgium.
Audrey MaudouxGIGA-Consciousness, Sensation & Perception Research Group, University of Liege, Liege, Belgium.
Marie-Elisabeth FaymonvilleDepartment of Algology and Palliative Care, University Hospital of Liege, Liege, Belgium.
Steven LaureysGIGA-Consciousness, Coma Science Group & Neurology Department, University Hospital of Liege, Liege, Belgium.
Olivia GosseriesGIGA-Consciousness, Coma Science Group & Neurology Department, University Hospital of Liege, Liege, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite recent advances in our understanding of consciousness disorders, accurate diagnosis of severely brain-damaged patients is still a major clinical challenge. We here present the case of a patient who was considered in an unresponsive wakefulness syndrome/vegetative state for 20 years. Repeated standardized behavioral examinations combined to neuroimaging assessments allowed us to show that this patient was in fact fully conscious and was able to functionally communicate. We thus revised the diagnosis into an incomplete locked-in syndrome, notably because the main brain lesion was located in the brainstem. Clinical examinations of severe brain injured patients suffering from serious motor impairment should systematically include repeated standardized behavioral assessments and, when possible, neuroimaging evaluations encompassing magnetic resonance imaging and

Indexed as

disorders of consciousnessEEGlocked-in syndromemisdiagnosisMRIPETunresponsive wakefulness syndromevegetative state

Identifiers

PMID30233480
PMCPMC6127614

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.