ArticleInternational journal of chronic obstructive pulmonary disease2018
Life-Space mobility and clinical outcomes in COPD.
Article in International journal of chronic obstructive pulmonary disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.
- Investigating the prognostic value of digital mobility outcomes in patients with chronic obstructive pulmonary disease: a systematic literature review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2023Pooled it
- Efficacy of a long-term pulmonary rehabilitation maintenance program for COPD patients in a real-life setting: a 5-year cohort study.Respiratory research · 2021Trial
- Trajectories and associated factors of life-space in older patients following percutaneous coronary intervention: a mixed-methods study.Journal of health, population, and nutrition · 2026Article
- Life-Space Mobility Trajectories After Elective Surgery in Older Adults.JAMA network open · 2026Article
- Life-Space Mobility in Heart Failure With Preserved Ejection Fraction.Journal of cardiac failure - intersections · 2026Article
- Frailty and social, clinical and computed tomography imaging factors in COPD: a multicentre study.ERJ open research · 2026Article
- Factors associated with life-space mobility in older adults with chronic respiratory disease: IMIAS study.Frontiers in rehabilitation sciences · 2026Article
- Elderly Activity Life-Space Envelopes (EASE): Development and Feasibility of a Comprehensive, Integrated Protocol for Life-Space Mobility Research in Population Health.JMIR research protocols · 2025Article
- Grip strength and cognitive function of older adults through the chain mediating effect of life space mobility and depression.Scientific reports · 2025Article
- Prevalence and correlates of restricted community mobility in a population-based cohort of adults with systemic lupus erythematosus.Lupus science & medicine · 2025Article
- Perceived Stress is Associated with Health Outcomes, Platelet Activation, and Oxidative Stress in COPD.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2025Article
- Article
- Identifying priority challenges of older adults with COPD: A multiphase intervention refinement study.Journal of the American Geriatrics Society · 2024Article
- Relationships between life-space mobility, physical function, and empowerment in patients with chronic obstructive pulmonary disease.Journal of physical therapy science · 2024Article
- Impact of COVID-19 Vaccine Rollout on Mental Health, Social Determinants of Health, and Attitudes Among Individuals With COPD.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2024Article
- Dynamic changes in quality of life in older patients with chronic obstructive pulmonary disease: a 7-year follow up.Health and quality of life outcomes · 2024Article
- Project EPIC (Empowering People to Independence in COPD): Study protocol for a hybrid effectiveness-implementation pilot randomized controlled trial of telephonic, geriatrics-palliative care nurse-coaching in older adults with COPD and their family caregivers.Contemporary clinical trials · 2024Article
- Restricted life-space mobility impacts physical but not mental quality of life in older cancer survivors.Cancer medicine · 2024Article
- National Prevalence of Social Isolation and Loneliness in Adults with Chronic Obstructive Pulmonary Disease.Annals of the American Thoracic Society · 2023Article
- Impact of an INtervention to increase MOBility in older hospitalized medical patients (INTOMOB): Study protocol for a cluster randomized controlled trial.BMC geriatrics · 2023Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Background: Social isolation is a common experience in patients with COPD but is not captured by existing patient-reported outcomes, and its association with clinical outcomes is unknown. Methods: We prospectively enrolled adults with stable COPD who completed the University of Alabama at Birmingham Life Space Assessment (LSA) (range: 0-120, restricted Life-Space mobility: ≤60 and a marker of social isolation in older adults); six-minute walk test (6MWT), and the University of California at San Diego Shortness of Breath Questionnaire, COPD Assessment Test, and Hospital Anxiety and Depression Scale. The occurrence of severe exacerbations (emergency room visit or hospitalization) was recorded by review of the electronic record up to 1 year after enrollment. We determined associations between Life-Space mobility and clinical outcomes using regression analyses. Results: Fifty subjects had a mean ± SD %-predicted FEV Conclusion: Restricted Life-Space mobility predicts severe exacerbations and is associated with reduced exercise tolerance, more severe dyspnea, reduced quality of life, and greater depressive symptoms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.