Evidence map›Paper›PMID 30232694›Full record

ReviewJournal of gastrointestinal cancer2018

Faecal Occult Blood Point-of-Care Tests.

Barbara Kościelniak-Merak, Branimir Radosavljević, Andrzej Zając, Przemysław J Tomasik

Abstract readComparative StudyReview
In one paragraph

Review in Journal of gastrointestinal cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Epidemiology and early screening strategies for colorectal cancer in China.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2023
    Article
  4. Review
  5. Novel Diagnostic Biomarkers in Colorectal Cancer.International journal of molecular sciences · 2022
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Barbara Kościelniak-MerakDepartment of Clinical Biochemistry, Institute of Pediatrics, Jagiellonian University Medical College, Wielicka St 265, 30-663, Cracow, Poland.
Branimir RadosavljevićInstitute of Chemistry in Medicine "Prof. dr Petar Matavulj", Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
Andrzej ZającDepartment of Pediatric Surgery, Jagiellonian University Medical College, Cracow, Poland.
Przemysław J TomasikDepartment of Clinical Biochemistry, Institute of Pediatrics, Jagiellonian University Medical College, Wielicka St 265, 30-663, Cracow, Poland. p.tomasik@uj.edu.pl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarly detection of colorectal cancer decreases the risk of mortality. Faecal occult blood tests (FOBT) are recognised as a useful tool for colorectal cancer screening. These non-invasive, rapid, and easy-to-carry assays are very often used as a point-of-care test and for self-testing. On the market, there are various types of FOB tests available, including chemical and immunochromatographic tests, which are based on different detection methods and differ in their sensitivity and specificity.

conclusionsClinicians should be aware of the causes of false-negative and false-positive test results, which can vary depending on the test. Additionally, stool sampling bias may be a source of error and must be considered by the clinician. The current FOBT methods are subject to various interfering factors; items such as proper preparation of the patient prior to testing or the clinician's knowledge of testing limitations are key in correct interpreting results. Novel technologies such as FOBT DNA tests, micro RNA tests, and biochips equipped with bacteria can indicate bleeding from the gastrointestinal tract and improve diagnostics process.

Indexed as

Occult BloodPoint-of-Care SystemsBiomarkers, TumorBiosensing TechniquesColonoscopyColorectal NeoplasmsDNAEarly Detection of CancerFalse Negative ReactionsFalse Positive ReactionsFecesHumansMass ScreeningRNASensitivity and SpecificityBiomarkers, TumorDNARNAColorectal cancerImmunochemistryOccult bloodPoint-of-careScreeningStool sampling

Identifiers

PMID30232694
PMCPMC6208834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.