Trial reportClinical oral investigations2019
Evaluation of the efficacy of calcium silicate vs. glass ionomer cement indirect pulp capping and restoration assessment criteria: a randomised controlled clinical trial-2-year results.
Trial report in Clinical oral investigations, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02201641 (Efficacy of Calcium Silicate Pulp-capping; a Randomized Controlled Clinical Trial), which is not on this map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Calcium Silicate Pulp-capping; a Randomized Controlled Clinical Trial
Who cites it
21 citing papers in PubMed, 65 citations in OpenAlex.
- Three-Year Clinical and Economic Evaluation of Selective Caries Removal and Full Pulpotomy for Extensive Caries: An Exploratory Randomised Controlled Trial.International endodontic journal · 2026Trial
- Calcium silicate liner versus no liner in selective caries removal: a one-year randomized clinical trial.BMC oral health · 2026Trial
- Outcomes of Direct Pulp Capping After Carious Excavation of Deep Caries on Permanent Mature Teeth: An Ancillary Study Derived From A Randomised Clinical Trial.European endodontic journal · 2025Trial
- The clinical performance of monoshade resin composite as posterior restoration: a randomized controlled clinical trial.Scientific reports · 2025Trial
- Physicochemical and remineralisation properties of calcium silicate and glass ionomer cements applied in simulated caries-affected dentine.European journal of oral sciences · 2026Article
- Clinical Outcomes of Immediate and Delayed Composite Restorations After Pulp Capping with Biodentine: A Systematic Literature Review.Journal of functional biomaterials · 2026Review
- Directed Self-Assembly of Magnetic Bioceramic Deep Inside Dentinal Tubules May Alleviate Dental Hypersensitivity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Clinical and radiographic success of pulpotomy and pulpectomy in primary and permanent teeth: a Systematic Review and Meta-Analysis.Journal of clinical and experimental dentistry · 2024Review
- Adrenaline in pulp capping treatment of reversible pulpitis.World journal of clinical cases · 2024Article
- Article
- Five-Year Clinical Performance of Complex Class II Resin Composite and Amalgam Restorations-A Retrospective Study.Dentistry journal · 2023Article
- Assessment of the remineralisation induced by contemporary ion-releasing materials in mineral-depleted dentine.Clinical oral investigations · 2022Article
- A Bibliometric Analysis (2010-2020) of the Dental Scientific Literature on Chemo-Mechanical Methods of Caries Removal Using Carisolv and BRIX3000.Medicina (Kaunas, Lithuania) · 2022Review
- Present status and future directions: Hydraulic materials for endodontic use.International endodontic journal · 2022Review
- Commercially Available Ion-Releasing Dental Materials and Cavitated Carious Lesions: Clinical Treatment Options.Materials (Basel, Switzerland) · 2021Review
- An Evaluation on Deep Caries Removal Method and Management Performed by Undergraduate Dental Students: A Malaysia Experience.European journal of dentistry · 2021Article
- Detection of Inflammatory and Homeostasis Biomarkers after Selective Removal of Carious Dentin-An In Vivo Feasibility Study.Journal of clinical medicine · 2021Article
- Preserving pulp vitality: part two - vital pulp therapies.British dental journal · 2021Review
- Preserving pulp vitality: part one - strategies for managing deep caries in permanent teeth.British dental journal · 2021Article
- Self-Limiting versus Rotary Subjective Carious Tissue Removal: A Randomized Controlled Clinical Trial-2-Year Results.Journal of clinical medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesAssess calcium silicate cement (Biodentine™) vs. glass ionomer cement (Fuji IX™, control) as indirect pulp capping (IPC) materials in patients with reversible pulpitis after a 2-year follow-up. Evaluate the integrity of the overlying resin composite restorations using modified USPHS criteria and FDI criteria. Investigate the sensitivity of the modified USPHS criteria compared to the FDI criteria in the assessment of the restorations. MATERIALS AND
methodsSeventy-two restorations (36 Biodentine™, 36 Fuji IX™) were placed randomly in 53 patients. Periapical radiographs were taken at pre-treatment (T0), 12-month (T12), and 24-month (T24) review. Restorations were assessed using the modified USPHS and FDI criteria at T12 and T24.
resultsAt 24 months, 15 teeth had failed to maintain vitality (6 Biodentine™, 9 Fuji IX™). Clinical success rate of IPC for both materials was 72% and is related to the intensity of reversible pulpitis symptoms. No difference was found between T12 and T24 in the periapical (PA) radiographs and in the integrity of the resin composite restorations overlying Biodentine™ compared to Fuji IX™. There was no difference in the efficacy of the USPHS criteria compared to the FDI criteria in the assessment of the resin composite restorations.
conclusionsBiodentine™ and Fuji IX™ were clinically effective when used as IPC materials in teeth with reversible pulpitis at T24. Resin composite restorations overlying both materials performed well at T24. Using the USPHS or FDI criteria is equally efficient at T24; however, longer term follow-up is needed to establish whether there are sensitivity differences between these assessment criteria. CLINICAL SIGNIFICANCE: Teeth with deep carious lesions approaching the pulp and with signs of reversible pulpitis can be treated successfully by indirect pulp capping using either Biodentine™ or Fuji IX™. Using the USPHS or FDI criteria to assess restorations is equally effective at 2 years.
trial registrationNCT02201641.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.