Evidence map›Paper›PMID 30232586›Full record

ReviewCurrent osteoporosis reports2018

Micro-Finite Element Analysis of the Proximal Femur on the Basis of High-Resolution Magnetic Resonance Images.

Chamith S Rajapakse, Gregory Chang

Abstract readReview
In one paragraph

Review in Current osteoporosis reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Chamith S RajapakseDepartments of Radiology and Orthopaedic Surgery, University of Pennsylvania, 3400 Spruce Street, 1 Founders Building, Philadelphia, PA, 19104, USA. chamith@pennmedicine.upenn.edu.
Gregory ChangDepartment of Radiology, New York University, 426 1st Avenue, New York, NY, 10010, USA.
New York University · USUniversity of Pennsylvania · US

Funding

MRI of Proximal Femur Microarchitecture as a Biomarker of Bone QualityR01AR066008 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHANG, GREGORY · 2014 to 2018
$2.8M
MRI of Proximal Femur Bone Quality for Monitoring Short-Term Response to Osteoporosis TherapyR01AR073851 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHANG, GREGORY · 2019 to 2023
$2.8M
Translation of Hip Microarchitectural Assessment Technology to the Clinic to Diagnose Glucocorticoid-Induced OsteoporosisR01AR070131 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHANG, GREGORY · 2016 to 2020
$2.7M
Clinical Assessment of Hip Fracture Biomechanics using MRIR01AR068382 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI RAJAPAKSE, CHAMITH SUDESH · 2015 to 2019
$1.8M
NIAMS NIH HHS R01 AR066008NIAMS NIH HHS R01 AR068382NIAMS NIH HHS R01 AR070131NIAMS NIH HHS R01 AR073851
6 · The paper itself

Abstract

purpose of reviewHip fractures have catastrophic consequences. The purpose of this article is to review recent developments in high-resolution magnetic resonance imaging (MRI)-guided finite element analysis (FEA) of the hip as a means to determine subject-specific bone strength. RECENT

findingsDespite the ability of DXA to predict hip fracture, the majority of fractures occur in patients who do not have BMD T scores less than - 2.5. Therefore, without other detection methods, these individuals go undetected and untreated. Of methods available to image the hip, MRI is currently the only one capable of depicting bone microstructure in vivo. Availability of microstructural MRI allows generation of patient-specific micro-finite element models that can be used to simulate real-life loading conditions and determine bone strength. MRI-based FEA enables radiation-free approach to assess hip fracture strength. With further validation, this technique could become a potential clinical tool in managing hip fracture risk.

Indexed as

Finite Element AnalysisAbsorptiometry, PhotonBone DensityFemurHip FracturesHumansImage EnhancementMagnetic Resonance ImagingBone strengthFinite element analysisHipMRIProximal femur

Identifiers

PMID30232586
PMCPMC6234089
OpenAlexW2889789592

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.