Evidence map›Paper›PMID 30232518›Full record

ArticleNeuroradiology2018

Conventional, diffusion, and permeability MR findings in ocular medulloepithelioma.

Paolo Galluzzi, Tommaso Casseri, Alfonso Cerase, Daria Guglielmucci, Paolo Toti, Thedora Hadjistilianou

Abstract read
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In one paragraph

Article in Neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Guideline
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Paolo GalluzziNeuroImaging and NeuroInterventional Unit, Azienda Ospedaliera e Universitaria, Senese, Siena, Italy. galluzzip@libero.it.
Tommaso CasseriRadiology Unit, University of Siena, Siena, Italy.
Alfonso CeraseNeuroImaging and NeuroInterventional Unit, Azienda Ospedaliera e Universitaria, Senese, Siena, Italy.
Daria GuglielmucciPediatric Unit, Azienda Ospedaliera e Universitaria Senese, Siena, Italy.
Paolo TotiDepartment of Pathology, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Thedora HadjistilianouDepartment of Ophthalmology, Referral Center for Retinoblastoma, Azienda Ospedaliera Universitaria Senese, Siena, Italy.
Azienda Ospedaliera Universitaria Senese · ITUniversity of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe the neuroradiological features of intraocular medulloepithelioma.

methodsWe retrospectively analyzed the clinical, histopathological, and MRI data of five children with medulloepithelioma. In addition to conventional images, DWI was performed in four patients and mean ADC was calculated; this was limited to the technique of this cohort of patients. DCE was performed in all patients. This is the first paper that presents diffusion and perfusion characteristics of medulloepithelioma.

resultsFour tumors were malignant teratoid variants, two non-teratoid variants. Tumors were hyperintense on T1-weighted images and hypointense on T2-weighted images. Calcifications were detectable in two out of five tumors. Cavities were detectable in three out of five tumors. All tumors showed some degree of enhancement. The mean ADC of all four patients was 1.156 ± 242.75 × 10

conclusionConventional MR findings were similar to previously reported cases. Mean ADCs were moderately high. TICs showed slow increase and presence of wash out. K-trans, AUC, VE, and TME were higher in teratoid variants. Permeability parameters in differential diagnosis with lesions mimicking medulloepithelioma need further investigations.

Indexed as

Brain NeoplasmsChildChild, PreschoolContrast MediaDiagnosis, DifferentialDiffusion Magnetic Resonance ImagingEcho-Planar ImagingFemaleHumansImage EnhancementImage Interpretation, Computer-AssistedInfantInfant, NewbornMagnetic Resonance ImagingMaleMeglumineContrast Mediagadoterate meglumineMeglumineOrganometallic CompoundsDifferential diagnosisDiffusionMedulloepitheliomaPerfusionPermeability

Identifiers

PMID30232518
OpenAlexW2889924608

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.