ArticleInternational journal of obesity (2005)2019
Maternal body mass index, gestational weight gain, and childhood abdominal, pericardial, and liver fat assessed by magnetic resonance imaging.
Article in International journal of obesity (2005), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Pooled it
- First 1000 Days Strategies to Prevent Childhood Obesity: A Narrative Review and Recommendations From the EndObesity Consortium.Pediatric obesity · 2026Review
- Article
- Associations of childhood BMI, general and visceral fat mass with metabolite profiles at school-age.International journal of obesity (2005) · 2024Article
- Maternal iron status in early pregnancy and childhood body fat measures and cardiometabolic risk factors: A population-based prospective cohort.The American journal of clinical nutrition · 2023Article
- Maternal Cardiovascular Health in Early Pregnancy and Childhood Brain Structure.Journal of the American Heart Association · 2022Article
- Body fat, pericardial fat, liver fat and arterial health at age 10 years.Pediatric obesity · 2022Article
- Maternal carbohydrate intake during pregnancy is associated with child peripubertal markers of metabolic health but not adiposity.Public health nutrition · 2022Article
- Early rapid weight gain, parental body mass index and the association with an increased waist-to-height ratio at 5 years of age.PloS one · 2022Article
- Body fat, cardiovascular risk factors and brain structure in school-age children.International journal of obesity (2005) · 2021Article
- Maternal Early-Pregnancy Glucose Concentrations and Liver Fat Among School-Age Children.Hepatology (Baltimore, Md.) · 2021Article
- Associations of maternal diet and nutritional status with offspring hepatic steatosis in the Avon longitudinal study of parents and children.BMC nutrition · 2021Article
- Associations of Early Pregnancy and Neonatal Circulating Folate, Vitamin B-12, and Homocysteine Concentrations with Cardiometabolic Risk Factors in Children at 10 y of Age.The Journal of nutrition · 2021Article
- Associations of maternal early-pregnancy dietary glycemic index with childhood general, abdominal and ectopic fat accumulation.Clinical nutrition (Edinburgh, Scotland) · 2021Article
- Phthalate and Bisphenol Urinary Concentrations, Body Fat Measures, and Cardiovascular Risk Factors in Dutch School-Age Children.Obesity (Silver Spring, Md.) · 2021Article
- Fetal exposure to phthalates and bisphenols and childhood general and organ fat. A population-based prospective cohort study.International journal of obesity (2005) · 2020Article
- Developmental overnutrition and obesity and type 2 diabetes in offspring.Diabetologia · 2019Review
- Risk Factors for Childhood Overweight and Obesity in Ukraine and GermanyJournal of clinical research in pediatric endocrinology · 2019Article
- Parental obesity programs pancreatic cancer development in offspring.Endocrine-related cancer · 2019Article
- Nutrition During Pregnancy, Lactation and Early Childhood and its Implications for Maternal and Long-Term Child Health: The Early Nutrition Project Recommendations.Annals of nutrition & metabolism · 2019Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesMaternal obesity and excessive gestational weight gain are associated with an increased risk of obesity in offspring. It remains unclear whether maternal adiposity also affects organ fat, which has important adverse cardiometabolic health consequences and whether the associations reflect intrauterine causal mechanisms. We examined the associations of parental pre-pregnancy body mass index (BMI) and gestational weight gain with general, abdominal, pericardial, and liver fat in 10-year-old children. SUBJECTS/
methodsIn a population-based prospective cohort study among 2354 parents and their children, we obtained pre-pregnancy maternal and paternal BMI and gestational weight gain and offspring BMI, fat mass index (total fat/height
resultsA 1-standard deviation score (SDS) higher maternal pre-pregnancy BMI was associated with higher childhood BMI (difference 0.32 (95% confidence interval (CI) 0.28, 0.36) SDS), fat mass index (difference 0.28 (95% CI 0.24, 0.31) SDS), subcutaneous fat index (difference 0.26 (95% CI 0.22, 0.30) SDS), visceral fat index (difference 0.24 (95% CI 0.20, 0.28) SDS), pericardial fat index (difference 0.12 (95% CI 0.08, 0.16) SDS), and liver fat fraction (difference 0.15 (95% CI 0.11, 0.19) SDS). After conditioning each MRI adiposity measure on BMI at 10 years, higher maternal pre-pregnancy BMI remained associated with higher childhood subcutaneous and visceral fat indices. Smaller but not statistically different effect estimates were observed for paternal BMI. Gestational weight gain was not consistently associated with organ fat.
conclusionsHigher maternal pre-pregnancy BMI, but not gestational weight gain, was associated with higher general and organ fat. Similar associations of pre-pregnancy maternal and paternal BMI with offspring adiposity suggest a role of family shared lifestyle factors and genetics.
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