Evidence map›Paper›PMID 30232173›Full record

ArticleDevelopment (Cambridge, England)2018

Single-cell murine genetic fate mapping reveals bipotential hepatoblasts and novel multi-organ endoderm progenitors.

Gabriel K El Sebae, Joseph M Malatos, Mary-Kate E Cone, Siyeon Rhee, Jesse R Angelo, Jesse Mager, Kimberly D Tremblay

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Fetal liver development and implications for liver disease pathogenesis.Nature reviews. Gastroenterology & hepatology · 2023
    Review
  5. Article
  6. Review
  7. Lgr5Development (Cambridge, England) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Gabriel K El SebaeDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA.
Joseph M MalatosDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA.
Mary-Kate E ConeDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA.
Siyeon RheeDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA.
Jesse R AngeloDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA.
Jesse MagerDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA.ORCID 0000-0002-4123-0633
Kimberly D TremblayDepartment of Veterinary and Animal Sciences, University of Massachusetts, Amherst, MA 01003, USA kdtrembl@umass.edu.ORCID 0000-0002-3059-9910
University of Massachusetts Amherst · US

Funding

Understanding liver bud emergence, formation and potentialR01DK087753 · NIDDK · UNIVERSITY OF MASSACHUSETTS AMHERST · PI TREMBLAY, KIMBERLY D · 2010 to 2014
$1.5M
NIDDK NIH HHS R01 DK087753
6 · The paper itself

Abstract

The definitive endoderm (DE) is the embryonic germ layer that forms the gut tube and associated organs, including thymus, lungs, liver and pancreas. To understand how individual DE cells furnish gut organs, genetic fate mapping was performed using the

Indexed as

Chromosome MappingSingle-Cell AnalysisAnimalsBile DuctsCell LineageClone CellsEmbryo, MammalianEndodermEpithelial CellsFemaleHepatocytesMaleMice, Inbred C57BLOrgan SpecificityStem CellsDefinitive endodermHepatoblastLineage tracingLiverMouse

Identifiers

PMID30232173
PMCPMC6198474
OpenAlexW2890989580

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.