Evidence map›Paper›PMID 30232132›Full record

ArticleJournal of clinical microbiology2018

Specificity of QuantiFERON-TB Plus, a New-Generation Interferon Gamma Release Assay.

S A R Siegel, M Cavanaugh, J H Ku, L M Kawamura, K L Winthrop

Open access · bronzeAbstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Comparing the Diagnostic Performance of QuantiFERON-TB Gold Plus to Other Tests of Latent Tuberculosis Infection: A Systematic Review and Meta-analysis.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2021
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Tuberculosis Infection in Children and Adolescents.Pathogens (Basel, Switzerland) · 2022
    Review
  7. Article
  8. Article
  9. Article
  10. Phenotype Definition for "Resisters" toFrontiers in immunology · 2021
    Review
  11. Interferon-γ and IL-10 Release Assay for Patients with Ocular Toxoplasmosis.The American journal of tropical medicine and hygiene · 2020
    Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

S A R SiegelSchool of Public Health, Oregon Health & Science University-Portland State University, Portland, Oregon, USA siegels@ohsu.edu.ORCID 0000-0001-8249-2632
M CavanaughOregon State Public Health Laboratory, Hillsboro, Oregon, USA.
J H KuSchool of Public Health, Oregon Health & Science University-Portland State University, Portland, Oregon, USA.
L M KawamuraQiagen, Germantown, Maryland, USA.
K L WinthropSchool of Public Health, Oregon Health & Science University-Portland State University, Portland, Oregon, USA.
Portland State University · USOregon State Hospital · USQiagen (United States) · US

Funding

Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4M
NCATS NIH HHS UL1 TR002369
6 · The paper itself

Abstract

Interferon gamma release assays (IGRAs) are important tools in identifying prior tuberculosis exposure. The new-generation QuantiFERON-TB Gold Plus (QFT-Plus) assay, recently approved for use in the United States, differs from the current-generation QFT Gold-In-Tube (QFT-GIT) assay with the addition of a second antigen tube that also contains novel CD8

Indexed as

Reagent Kits, DiagnosticAdolescentAdultAgedBacteriological TechniquesFemaleHumansInterferon-gammaInterferon-gamma Release TestsLatent TuberculosisMaleMiddle AgedMycobacterium Infections, NontuberculousMycobacterium tuberculosisSensitivity and SpecificityTuberculosisInterferon-gammaReagent Kits, Diagnosticdiagnosticlatent tuberculosis infectionnontuberculous mycobacterial infection

Identifiers

PMID30232132
PMCPMC6258840
OpenAlexW2889886508

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.