Evidence map›Paper›PMID 30232112›Full record

ArticleBMJ open2018

The UALE project: a cross-sectional approach for trends in HIV/STI prevalence among key populations attending STI clinics in Guatemala.

Juan Ignacio García, Meritxell Sabidó, Mikhail Nikiforov, Adriana Smith, Gabriela Hernández, Rudy Ortiz, Luis Ardani, Alba Cajas, Elsy Camey, Jordi B Torrelles and 5 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Anatomic site distribution ofIndian journal of sexually transmitted diseases and AIDS
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 6 institutions in 3 countries.

Juan Ignacio GarcíaFundació Sida i Societat, Technical Advisor Unit (UAT), Hospital Nacional de Escuintla, Escuintla, Guatemala.ORCID 0000-0001-8263-3140
Meritxell SabidóTransLab, Department of Medical Sciences, Universitat de Girona, Girona, Spain.
Mikhail NikiforovFundació Sida i Societat, Technical Advisor Unit (UAT), Hospital Nacional de Escuintla, Escuintla, Guatemala.
Adriana SmithFundació Sida i Societat, Technical Advisor Unit (UAT), Hospital Nacional de Escuintla, Escuintla, Guatemala.
Gabriela HernándezFundació Sida i Societat, Technical Advisor Unit (UAT), Hospital Nacional de Escuintla, Escuintla, Guatemala.
Rudy OrtizFundació Sida i Societat, Technical Advisor Unit (UAT), Hospital Nacional de Escuintla, Escuintla, Guatemala.
Luis ArdaniFundació Sida i Societat, Technical Advisor Unit (UAT), Hospital Nacional de Escuintla, Escuintla, Guatemala.
Alba CajasFundació Sida i Societat, Technical Advisor Unit (UAT), Hospital Nacional de Escuintla, Escuintla, Guatemala.
Elsy CameyFundació Sida i Societat, Technical Advisor Unit (UAT), Hospital Nacional de Escuintla, Escuintla, Guatemala.
Jordi B TorrellesTexas Biomedical Research Institute, San Antonio, Texas, USA.
Shu-Hua WangDepartment of Internal Medicine, Division of Infectious Diseases. The Ohio State University, Columbus, Ohio, USA.
Colin N J CampbellTB Section, National Infection Service, Public Health England, London, UK.
Cinta FolchCenter for Epidemiological Studies on HIV/AIDS and STI of Catalonia (CEEISCAT), Generalitat de Catalunya, Badalona, Spain.
Jordi CasabonaFundació Sida i Societat, Technical Advisor Unit (UAT), Hospital Nacional de Escuintla, Escuintla, Guatemala.
UALE Study Group
Universitat Autònoma de Barcelona · ESGeneralitat de Catalunya · ESPublic Health England · GBTexas Biomedical Research Institute · USThe Ohio State University · USUniversitat de Girona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe and compare trends in prevalence, sexual behaviour and HIV transmission knowledge data related to sexually transmitted infections (STI) and HIV in patients attending three STI clinics over an 8-year period in Escuintla Department, Guatemala.

methodsSTI clinic attendees were classified into transmission groups as follows: female sex workers (FSW), men who have sex with men (MSM) and 'high-risk heterosexuals' (HRH). Annual cross-sectional analysis and multivariable Poisson regression adjusted for sociodemographic variables were used for prevalence comparisons and adjusted prevalence trends for HIV/STI outcomes and used for adjusted trends in proportions in sexual behaviour and HIV transmission knowledge outcomes. Endocervical swabs were obtained to detect trichomonas, chlamydia and neisseria infections. Serologies for syphilis and HIV were performed using rapid tests. For reactive HIV samples, positivity was confirmed by an ELISA. All reactive syphilis samples were further confirmed for diagnosis of active syphilis disease.

resultsFrom a total of 4027 clinic attendees, 3213 (79.78%) were FSW, 229 (5.69%) were MSM and 585 (14.53%) were HRH. The proportion of FSW, MSM and HRH who had a single visit was 56.42%, 57.23% and 91.10%, respectively. Overall, HIV prevalence was 2.10% in FSW, 8.17% in MSM and 4.12% in HRH. Prevalence trends in HIV and syphilis decreased in FSW. Prevalence trends in gonorrhoea did not decrease over time neither in FSW nor in HRH. Chlamydia and trichomonas infections in HRH showed an increase prevalence trend. In FSW, trends in condom use in last sexual intercourse with regular and occasional clients were above 93%.

conclusionsFSW show a decreasing trend in HIV, syphilis and chlamydia prevalence. Gonorrhoea prevalence in FSW and HRH did not decrease over time. HRH is a hard to engage population with low follow-up rates and high potential to act as a bridge population.

Indexed as

HIV InfectionsSexual BehaviorSexually Transmitted DiseasesAdultCross-Sectional StudiesFemaleGuatemalaHumansMaleMicrobiological TechniquesPrevalencePublic HealthRisk FactorsSexual and Gender MinoritiesSex Workersdiagnostic microbiologyepidemiologypublic healthsexual medicine

Identifiers

PMID30232112
PMCPMC6150151
OpenAlexW2892041485

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.