Observational studyBMJ open2018
Sarcopenic obesity associated with high-sensitivity C-reactive protein in age and sex comparison: a two-center study in South Korea.
Observational study in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 39 citations in OpenAlex.
- The association between composite dietary antioxidant index and sarcopenic obesity.Nutrition & metabolism · 2025Article
- Association between dietary inflammatory index and sarcopenia development in Polish population.Scientific reports · 2025Article
- The impact of elevated dietary inflammatory potential on sarcopenic obesity: evidence from two observational studies.Frontiers in nutrition · 2025Article
- Sex-Specific Association of Low Muscle Mass with Depression Status in Asymptomatic Adults: A Population-Based Study.Brain sciences · 2024Article
- Exploring the Association between Elevated Anxiety Symptoms and Low Skeletal Muscle Mass among Asymptomatic Adults: A Population-Based Study in Republic of Korea.Brain sciences · 2024Article
- Article
- Impact of Low Skeletal Muscle Mass and Obesity on Hearing Loss in Asymptomatic Individuals: A Population-Based Study.Healthcare (Basel, Switzerland) · 2022Article
- Sex Difference in Cutoff and Prevalence of Sarcopenia among 300,090 Urban Korean Population: Association with Metabolic Syndrome.Medicina (Kaunas, Lithuania) · 2022Article
- Increased Carcinoembryonic Antigen (CEA) Level Is Highly Associated with Low Skeletal Muscle Mass in Asymptomatic Adults: A Population-Based Study.Journal of clinical medicine · 2022Article
- Association between osteosarcopenia and coronary artery calcification in asymptomatic individuals.Scientific reports · 2022Article
- Association between Elevated Plasma Homocysteine and Low Skeletal Muscle Mass in Asymptomatic Adults.Endocrinology and metabolism (Seoul, Korea) · 2022Article
- Article
- COVID-19 and Obesity: Overlapping of Two Pandemics.Obesity facts · 2021Review
- Synergistic Effects and Sex Differences in Anthropometric Measures of Obesity and Elevated High-Sensitivity C-Reactive Protein Levels.International journal of environmental research and public health · 2020Article
- Obesity and COVID-19: A Fatal Alliance.Indian journal of clinical biochemistry : IJCB · 2020Review
- The fat mass, estimated glomerular filtration rate, and chronic inflammation in type 2 diabetic patients.Journal of clinical laboratory analysis · 2020Observational
- Phenotypes of Sarcopenic Obesity: Exploring the Effects on Peri-Muscular Fat, the Obesity Paradox, Hormone-Related Responses and the Clinical Implications.Geriatrics (Basel, Switzerland) · 2020Review
- Discriminating sarcopenia in overweight/obese male patients with heart failure: the influence of body mass index.ESC heart failure · 2020Article
- Polycystic ovary syndrome is a risk factor for sarcopenic obesity: a case control study.BMC endocrine disorders · 2019Article
- Association between sarcopenic obesity and higher risk of type 2 diabetes in adults: A systematic review and meta-analysis.World journal of diabetes · 2019Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo evaluate the association between high-sensitivity C-reactive protein (hs-CRP) and sarcopenic obesity, and to determine age or sex differences underlying the relationship between hs-CRP and sarcopenic obesity.
designObservational study.
participantsThe study included 237 838 participants whose body composition and hs-CRP were analysed at the two health promotion centres in South Korea. Participants were divided into four groups based on body composition: normal, obesity only, sarcopenia only and sarcopenic obesity. PRIMARY MEASURES: The levels of hs-CRP and proportion of participants with high (≥1.0 mg/L) hs-CRP. Sarcopenic obesity was defined as subjects fulfilling the criteria for sarcopenia (below 2 SD of mean of Skeletal Muscle Mass Index for young adults) and obesity (waist circumference ≥90 cm for men and ≥85 cm for women).
resultsThe level of hs-CRP was highest in the sarcopenic obesity group. Following adjustment for various confounders including age, sex, comorbidities, metabolic, health-related behaviour and demographic factors, the adjusted ORs (95% CI) for subjects with high hs-CRP associated with obesity, sarcopenia and sarcopenic obesity compared with normal group (reference) were 1.17 (1.05 to 1.31), 2.23 (1.21 to 4.07) and 3.23 (2.71 to 3.83), respectively. In age subgroup analyses, multivariate logistic regression analysis revealed that the association of high hs-CRP with sarcopenic obesity was stronger in younger (<60 years) participants than in older (≥60 years) participants (p for interaction <0.001). In subgroup analyses for sex, the association of high hs-CRP with sarcopenic obesity was higher in female participants than in males (p for interaction <0.001).
conclusionsThis study demonstrated that high level of hs-CRP was independently associated with sarcopenic obesity in Korean population. We found for the first time that there was a strong association between increased hs-CRP and sarcopenic obesity in female and younger (<60 years) subjects.
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