SynthesisBMJ open2018
Association between bronchopulmonary dysplasia and cerebral palsy in children: a meta-analysis.
Synthesis in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Cumulative Evidence for the Association of Thrombosis and the Prognosis of COVID-19: Systematic Review and Meta-Analysis.Frontiers in cardiovascular medicine · 2021Pooled it
- Maternal chorioamnionitis and neurodevelopmental outcomes in preterm and very preterm neonates: A meta-analysis.PloS one · 2018Pooled it
- Severe neonatal complications and long-term health-related quality of life in very preterm and/or very low birth weight survivors: evidence from the Dutch Project on preterm and small for gestational age cohort.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Do systemic steroids impact survival free of cerebral palsy in preterm infants at risk for bronchopulmonary dysplasia?Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Adrenomedullin overexpression protects mice from experimental bronchopulmonary dysplasia and associated pulmonary hypertension.American journal of physiology. Lung cellular and molecular physiology · 2025Article
- A Closer Look at Parental Narratives: A Qualitative Analysis of Parental Entries in Neonatal Research Diaries of Preterm Infants Participating in the REPORT-BPD Feasibility Study.Children (Basel, Switzerland) · 2025Article
- Comparative analysis of three bronchopulmonary dysplasia diagnostic criteria in predicting longterm neurodevelopmental outcomes in preterm infants.Scientific reports · 2025Article
- Systemic corticosteroid use and neurodevelopmental outcomes in preterm infants: a cohort study.World journal of pediatrics : WJP · 2025Article
- A rat model establishment of bronchopulmonary dysplasia-related lung & brain injury within 28 days after birth.BMC neuroscience · 2024Article
- Correlation between Bronchopulmonary Dysplasia and Cerebral Palsy in Children: A Comprehensive Analysis Using the National Inpatient Sample Dataset.Children (Basel, Switzerland) · 2024Article
- The impact of early tracheostomy on neurodevelopmental outcomes of infants with severe bronchopulmonary dysplasia exposed to postnatal corticosteroids.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Article
- The Relationship between General Movements and Risk Factors in Moderate-Late Preterm Infants: A Prospective Cohort Study.Journal of clinical medicine · 2023Article
- PPAR Gamma Receptor: A Novel Target to Improve Morbidity in Preterm Babies.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Phthalate exposure in the neonatal intensive care unit is associated with development of bronchopulmonary dysplasia.Environment international · 2023Article
- Effects of Chest Physiotherapy in Preterm Infants with Respiratory Distress Syndrome: A Systematic Review.Healthcare (Basel, Switzerland) · 2023Review
- Association between bronchopulmonary dysplasia and death or neurodevelopmental impairment at 3 years in preterm infants without severe brain injury.Frontiers in neurology · 2023Article
- Health-related quality of life of children born very preterm: a multinational European cohort study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023Article
- The Aryl Hydrocarbon Receptor (AHR): A Novel Therapeutic Target for Pulmonary Diseases?International journal of molecular sciences · 2022Review
- Anaesthesia and cerebral palsy.BJA education · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate the association between bronchopulmonary dysplasia (BPD) and the risk of cerebral palsy (CP) in children. DATA SOURCES: We used EMBASE, PubMed and Web of Science to conduct a meta-analysis of studies published before 1 September 2017, written in English whose titles or abstracts discussed an association between BPD and CP. STUDY SELECTION: Observational studies, for example, case-control and cohort studies were included. DATA EXTRACTION AND SYNTHESIS: All review stages were conducted by two reviewers independently. Data synthesis was undertaken via meta-analysis of available evidence. MAIN OUTCOMES AND MEASURES: The prevalence of developing CP was measured after exposure to BPD.
resultsAmong 1234 initially identified studies, we selected those that addressed an association between BPD and CP according to our preselected inclusion criteria. Our meta-analysis included 11 studies. According to a random effect model, BPD was significantly associated with CP (ORs 2.10; 95% CI 1.57 to 2.82) in preterm infants. Factors explaining differences in the study results included study design, the definition of BPD, the time of diagnosis of CP and whether the studies adjusted for potential confounders.
conclusionThis study suggests that BPD is a risk factor for CP. Further studies are required to confirm these results and to detect the influence of variables across studies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.