Evidence map›Paper›PMID 30231996›Full record

ArticleCell reports2018

The Drosophila Small Conductance Calcium-Activated Potassium Channel Negatively Regulates Nociception.

Kia C E Walcott, Stephanie E Mauthner, Asako Tsubouchi, Jessica Robertson, W Daniel Tracey

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Mechanical Nociception Assay inCold Spring Harbor protocols · 2025
    Article
  5. Nociception inCold Spring Harbor protocols · 2025
    Article
  6. Regulatory Action of Calcium and Calcium Channels in Pain Pathways.International journal of biological sciences · 2025
    Review
  7. Review
  8. Loss ofThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
  9. eLife · 2022
    Article
  10. Article
  11. Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Kia C E WalcottDepartment of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, USA.
Stephanie E MauthnerGill Center for Biomolecular Research, Indiana University, Bloomington, IN, USA; Department of Biology, Indiana University, Bloomington, IN, USA.
Asako TsubouchiDepartment of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
Jessica RobertsonDepartment of Cell Biology, Duke University Medical Center, Durham, NC, USA.
W Daniel TraceyGill Center for Biomolecular Research, Indiana University, Bloomington, IN, USA; Department of Biology, Indiana University, Bloomington, IN, USA; Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA; Department of Cell Biology, Duke University Medical Center, Durham, NC, USA. Electronic address: dtracey@indiana.edu.
Duke Medical Center · USDuke University Hospital · USIndiana University Bloomington · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Drosophila Transgenic RNAi Resource ProjectR01GM084947 · NIGMS · HARVARD MEDICAL SCHOOL · PI PERRIMON, NORBERT · 2008 to 2019
$9.8M
DROSOPHILA GENOMICS RESOURCE CENTERP40OD010949 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Andrew Zelhof · 2012 to 2026
$9.4M
A Genome-Wide Analysis of Nociception Molecules, from Expression to FunctionR01GM086458 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI TRACEY, WILLIAM D · 2011 to 2020
$2.6M
Genetic Analysis of Nociception in DrosophilaR01NS054899 · NINDS · DUKE UNIVERSITY · PI TRACEY, WILLIAM D · 2007 to 2011
$1.7M
Genome-Wide Analysis of Ion Channels Required For MechanosensationR21DC010222 · NIDCD · DUKE UNIVERSITY · PI TRACEY, WILLIAM D · 2009 to 2010
$429k
NIDCD NIH HHS R21 DC010222NIGMS NIH HHS R01 GM084947NIGMS NIH HHS R01 GM086458NIH HHS P40 OD010949NIH HHS P40 OD018537NINDS NIH HHS R01 NS054899
6 · The paper itself

Abstract

Inhibition of nociceptor activity is important for the prevention of spontaneous pain and hyperalgesia. To identify the critical K

Indexed as

NociceptionAnimalsCalciumDendritesDrosophila melanogasterDrosophila ProteinsSmall-Conductance Calcium-Activated Potassium ChannelsCalciumDrosophila ProteinsSmall-Conductance Calcium-Activated Potassium Channelsbehaviorcalcium imaginggenetic screenKv channelnociceptionpainphysiologypotassium channelsmall conductance calcium-activated potassium channel

Identifiers

PMID30231996
PMCPMC6454897
OpenAlexW2891914778

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.