ArticleCell reports2018
Spatial Separation of Mitochondrial Calcium Uptake and Extrusion for Energy-Efficient Mitochondrial Calcium Signaling in the Heart.
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Article in Cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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42citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
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Who cites it
42 citing papers in PubMed, 70 citations in OpenAlex.
- Asymmetric distribution of mitochondrial CaExperimental & molecular medicine · 2026Article
- Mitochondrial calcium regulates lipid metabolism by modulating tethering of mitochondria to lipid droplets.The EMBO journal · 2026Article
- Mitochondria: the central hub linking exercise to enhanced cardiac function.Frontiers in physiology · 2026Review
- Cardiac SR-Mitochondria Contacts-Impact on Cardiac Physiology and Mitochondrial Fitness.Cells · 2025Review
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- Ultrastructure analysis of mitochondria, lipid droplet and sarcoplasmic reticulum apposition in human heart failure.Journal of molecular and cellular cardiology plus · 2025Article
- A simulation study on the role of mitochondria-sarcoplasmic reticulum CaThe Journal of physiology · 2025Article
- Article
- Sarcoplasmic reticulum-mitochondria microdomains: hugging and kissing in the heart.American journal of physiology. Cell physiology · 2025Review
- The roles of mitochondria in global and local intracellular calcium signalling.Nature reviews. Molecular cell biology · 2025Review
- Integrating Mitochondrial Biology into Innovative Cell Therapies for Neurodegenerative Diseases.Brain sciences · 2024Review
- Mitochondrial CaJACC. Basic to translational science · 2024Article
- Intracellular to Interorgan Mitochondrial Communication in Striated Muscle in Health and Disease.Endocrine reviews · 2023Review
- Enhanced Mitochondria-SR Tethering Triggers Adaptive Cardiac Muscle Remodeling.Circulation research · 2023Article
- Mitochondrial sodium/calcium exchanger NCLX regulates glycolysis in astrocytes, impacting on cognitive performance.Journal of neurochemistry · 2023Article
- Efficacy of Dangua Fang on endothelial cells damaged by oxidative stress.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2022Article
- Sarcomere maturation: function acquisition, molecular mechanism, and interplay with other organelles.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Spatial and Functional Crosstalk between the Mitochondrial NaInternational journal of molecular sciences · 2022Article
- VDAC2 as a novel target for heart failure: CaCell calcium · 2022Review
- A CaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Sergio De La FuenteMitoCare Center for Mitochondrial Imaging Research and Diagnostics, Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Jonathan P LambertCenter for Translational Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA.
Zuzana NichtovaMitoCare Center for Mitochondrial Imaging Research and Diagnostics, Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Celia Fernandez SanzCenter for Translational Medicine, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA.
John W ElrodCenter for Translational Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, PA 19140, USA.
Shey-Shing SheuCenter for Translational Medicine, Department of Medicine, Thomas Jefferson University, Philadelphia, PA 19107, USA. Electronic address: shey-shing.sheu@jefferson.edu.
György CsordásMitoCare Center for Mitochondrial Imaging Research and Diagnostics, Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA. Electronic address: gyorgy.csordas@jefferson.edu.
Thomas Jefferson University · USTemple University · US
Funding
Small and large animal surgery, physiology and histologyP01HL134608 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI Raj Kishore · 2017 to 2026
$21.0MProject 3 Dysregulation of metabolic communication of oligodendrocytes and neurons by cocaine and TatP01DA037830 · NIDA · TEMPLE UNIV OF THE COMMONWEALTH · PI KHALILI, KAMEL · 2015 to 2019
$7.4MCa2+ and ROS Crosstalk Signaling in Cardiac MitochondriaR01HL093671 · NHLBI · UNIVERSITY OF ROCHESTER · PI SHEU, SHEY-SHING · 2010 to 2023
$5.1MMitochondria-SR Tethering: Its Role in Cardiac Bioenergetics and Ca2+ DynamicsR01HL122124 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI CSORDAS, GYORGY, SHEU, SHEY-SHING · 2014 to 2025
$4.0MMolecular composition of the mitochondrial calcium uniporter and cardiac pathophysiologyR01HL142271 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI ELROD, JOHN WILLIAM, HAJNOCZKY, GYORGY · 2018 to 2021
$3.0MDynamin-Related Protein Drp1 Regulates Cardiac Excitation-Contraction-Bioenergetics CouplingR01HL137266 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI SHEU, SHEY-SHING, WANG, WANG · 2018 to 2021
$2.5MStructural-functional zoning of the mitochondrion in cardiac Ca2+, ROS, and energetics regulationR01HL142864 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI CSORDAS, GYORGY, SHEU, SHEY-SHING · 2018 to 2021
$2.5MMechanisms of mitochondrial calcium exchange in heart failureR01HL123966 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI ELROD, JOHN WILLIAM · 2014 to 2018
$2.3MNovel Molecular Mechanisms of Programmed NecrosisR01HL136954 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI ELROD, JOHN WILLIAM · 2017 to 2020
$1.6MNHLBI NIH HHS P01 HL134608NHLBI NIH HHS R01 HL093671NHLBI NIH HHS R01 HL122124NHLBI NIH HHS R01 HL123966NHLBI NIH HHS R01 HL136954NHLBI NIH HHS R01 HL137266NHLBI NIH HHS R01 HL142271NHLBI NIH HHS R01 HL142864NIDA NIH HHS P01 DA037830
Abstract
Mitochondrial Ca
Indexed as
Calcium SignalingAnimalsCalciumCell LineMaleMembrane Potential, MitochondrialMiceMice, Inbred C57BLMitochondria, HeartMyocardiumRatsRats, Sprague-DawleySodiumCalciumSodiumCa2+ mitochondriacalcium signalingcardiac excitation-energetics couplingcardiac musclemitochondrial Ca2+ uniporter distributionmitochondria-sarcoplasmic reticulum contact sitesNCLX distribution
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LicenceCC BY-NC-ND
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.