ArticleMicrobiome2018
A metagenomics roadmap to the uncultured genome diversity in hypersaline soda lake sediments.
Article in Microbiome, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.
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Who cites it
88 citing papers in PubMed, 183 citations in OpenAlex.
- Genome mining of alkaliphilic cyanobacterial consortia: identification of biosynthetic gene clusters inApplied and environmental microbiology · 2026Article
- SuSha: A multi-model ensemble learning framework for predicting microbial salinity adaptation.Engineering microbiology · 2026Article
- Metagenomic insights into the taxonomic and metabolic diversity of the microbiome of Lake Karum in the Danakil Depression, Ethiopia.Environmental microbiome · 2026Article
- The Prokaryotic Community of Hypersaline Soils from the Odiel Saltmarshes: Culturomics Versus Metagenomics.Life (Basel, Switzerland) · 2026Article
- Unravelling Extremophilic Microbiome Diversity and Functional Dynamics in Hypersaline Environment.Microbial ecology · 2026Article
- Functional genetic potential of benthic microbial mat communities in Arctic, Antarctic, and sub-Antarctic lakes.FEMS microbiology ecology · 2026Article
- Physiology, functional genomics, and proteomics ofApplied and environmental microbiology · 2026Article
- Insights into microbial diversity affected by plant cover in athalassohaline ecosystem of el-hamra lake, wadi el-natrun, Egypt.World journal of microbiology & biotechnology · 2026Article
- Predictive functional profiling of 16S rRNA genes amplicons reveals bioremediation and sulfur metabolism capacity in thermophilic hot spring bacteriomes.Scientific reports · 2026Article
- Unveiling a Microbial Treasure Trove: Phylogenetic Diversity and Bioremediation Potential in a High-Altitude Andean Saline System.Microbial ecology · 2026Article
- Uncovering the Prokaryotic Diversity of Hypersaline Soils of Odiel Saltmarshes Natural Area Through Metagenome-Assembled Genomes.Microorganisms · 2026Article
- Genome-Resolved Approach of Guerrero Negro Hypersaline Microbial Mats Reveals the Metabolic Potential of Key Players in a Stratified Community.Environmental microbiology · 2025Article
- Extensive data mining uncovers novel diversity among members of the rare biosphere within the Thermoplasmatota.Microbiome · 2025Article
- Genomic characterisation of novel extremophile lineages from the thalassohaline lake Dziani Dzaha expands the metabolic repertoire of the PVC superphylum.Environmental microbiome · 2025Article
- Exceptionally high carbon fixation and nitrogen assimilation rates in microbial mats of an alkaline soda lake.The ISME journal · 2025Article
- Biogeography of soda lake microbiome and uneven cross-continent transition rates.Frontiers in microbiology · 2025Article
- Higher diversity of sulfur-oxidizing bacteria based on soxB gene sequencing in surface water than in spring in Wudalianchi volcanic group, NE China.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Metagenomics-assembled genomes reveal microbial metabolic adaptation to athalassohaline environment, the case Lake Barkol, China.Frontiers in microbiology · 2025Article
- Microbial dark matter spearheading the biogeochemical cycle in the Solar Lake of Taba, Egypt.Current research in microbial sciences · 2025Article
- Dispersal shapes compositional and functional diversity in aquatic microbial communities.mSystems · 2024Article
28 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 4 institutions in 4 countries.
Funding
Abstract
backgroundHypersaline soda lakes are characterized by extreme high soluble carbonate alkalinity. Despite the high pH and salt content, highly diverse microbial communities are known to be present in soda lake brines but the microbiome of soda lake sediments received much less attention of microbiologists. Here, we performed metagenomic sequencing on soda lake sediments to give the first extensive overview of the taxonomic diversity found in these complex, extreme environments and to gain novel physiological insights into the most abundant, uncultured prokaryote lineages.
resultsWe sequenced five metagenomes obtained from four surface sediments of Siberian soda lakes with a pH 10 and a salt content between 70 and 400 g L
conclusionsOur first sequencing effort of hypersaline soda lake sediment metagenomes led to two important advances. First, we showed the existence and obtained the first genomes of haloalkaliphilic members of the CPR and several hundred other novel prokaryote lineages. The soda lake CPR is a functionally diverse group, but the most abundant organisms in this study are likely fermenters with a possible role in primary carbon degradation. Second, we found evidence for the presence of the Wood-Ljungdahl pathway in many more taxonomic groups than those encompassing known homo-acetogens, sulfate-reducers, and methanogens. Since only few environmental metagenomics studies have targeted sediment microbial communities and never to this extent, we expect that our findings are relevant not only for the understanding of haloalkaline environments but can also be used to set targets for future studies on marine and freshwater sediments.
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