ArticleParasites & vectors2018
Revisiting the infectivity and pathogenicity of Cryptosporidium avium provides new information on parasitic sites within the host.
Article in Parasites & vectors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 23 citations in OpenAlex.
- Detection of Cryptosporidium and Giardia duodenalis in Reptiles in Thailand.Veterinary medicine and science · 2026Article
- Development of a field-deployable RPA-CRISPR/Cas12a assay for the detection of Cyclospora cayetanensis in human feces.Parasites & vectors · 2025Article
- Prevalence and Molecular Characterization ofPathogens (Basel, Switzerland) · 2025Article
- Newly fabricated zinc oxide nanoparticles loaded materials for therapeutic nano delivery in experimental cryptosporidiosis.Scientific reports · 2023Article
- Dominance of the zoonotic pathogen Cryptosporidium meleagridis in broiler chickens in Guangdong, China, reveals evidence of cross-transmission.Parasites & vectors · 2022Article
- Efficacy of clofazimine and nitazoxanide combination in treating intestinal cryptosporidiosis and enhancing intestinal cellular regeneration in immunocompromised mice.Food and waterborne parasitology · 2022Article
- Anticryptosporidium Efficacy ofCells · 2021Article
- Molecular identification and biological characterization of Cryptosporidium muris from camels (Camelus bactrianus) in China.Parasites & vectors · 2021Article
- Occurrence of Cryptosporidium and Giardia in wild birds from Qinghai Lake on the Qinghai-Tibetan Plateau, China.Parasitology research · 2021Article
- Article
- First Detection ofMicroorganisms · 2019Article
- Occurrence of a Cryptosporidium xiaoi-like genotype in peafowl (Pavo cristatus) in China.Parasitology research · 2019Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
backgroundCryptosporidium spp. are protozoans that cause diarrheal illness in humans and animals, including birds, worldwide. The present study was aimed to revisit the infectivity and pathogenicity of C. avium, recently considered to be a valid avian-infecting species of Cryptosporidium, and foster further understanding of its biological characteristics.
resultsResults showed that no Cryptosporidium oocysts were detected in the feces of experimentally inoculated BALB/c mice, Mongolian gerbils, quail or budgerigars within 30 days post-infection (dpi). Oocysts were first detected in feces of 3-day-old and 40-day-old hens at 8 and 9 dpi, respectively. In ducks infected with C. avium, oocysts were first detected at 9 dpi. Oocysts of infected animals were studied using a nested-polymerase chain reaction (PCR) technique for the SSU rRNA gene, actin gene, HSP70 gene and Cryptosporidium oocyst wall protein gene (COWP) detection. Restriction fragment length polymorphism (RFLP), using SspI and VspI restriction enzymes, was carried out to genotype the species and obtained amplification products were sequenced. Cryptosporidium developmental stages were found in the longitudinal plica of the bursa fabricii (BF) of hens, with high levels observed in histological sections and scanning electron microscopy. No pathological changes were observed.
conclusionsThese findings indicate that the bursa fabricii may be the primary site of C. avium infection. More biological data are needed to support the establishment of new species and contribute to the taxonomy of Cryptosporidium.
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