Evidence map›Paper›PMID 30231589›Full record

ReviewInternational journal of molecular sciences2018

Extracellular Vesicles in Bladder Cancer: Biomarkers and Beyond.

Yu-Ru Liu, Carlos J Ortiz-Bonilla, Yi-Fen Lee

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Review
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  7. Article
  8. Profiles of urinal exosomal miRNAs derived from bladder cancer.Central European journal of urology · 2024
    Article
  9. Review
  10. Review
  11. Review
  12. Article
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  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Yu-Ru LiuDepartment of Urology, University of Rochester Medical Center, Rochester, NY 14642, USA. yu-ru_liu@urmc.rochester.edu.
Carlos J Ortiz-BonillaDepartment of Urology, University of Rochester Medical Center, Rochester, NY 14642, USA. Carlos_ortizbonilla@urmc.rochester.edu.ORCID 0000-0002-6949-6193
Yi-Fen LeeDepartment of Urology, University of Rochester Medical Center, Rochester, NY 14642, USA. yifen_lee@urmc.rochester.edu.
University of Rochester Medical Center · US

Funding

Exosomes: A novel mechanism for bladder cancer tumorigenesis and progressionR01CA173986 · NCI · UNIVERSITY OF ROCHESTER · PI LEE, YI-FEN · 2014 to 2018
$1.8M
NCI NIH HHS NCI R01 CA173986NCI NIH HHS R01 CA173986
6 · The paper itself

Abstract

Tumor-derived extracellular vesicles (TEVs) are membrane-bound, nanosized vesicles released by cancer cells and taken up by cells in the tumor microenvironment to modulate the molecular makeup and behavior of recipient cells. In this report, we summarize the pivotal roles of TEVs involved in bladder cancer (BC) development, progression and treatment resistance through transferring their bioactive cargos, including proteins and nucleic acids. We also report on the molecular profiling of TEV cargos derived from urine and blood of BC patients as non-invasive disease biomarkers. The current hurdles in EV research and plausible solutions are discussed.

Indexed as

AnimalsBiomarkers, TumorDisease ProgressionExtracellular VesiclesHumansTumor MicroenvironmentUrinary BladderUrinary Bladder NeoplasmsBiomarkers, Tumorbiomarkersbladder cancerexosomeextracellular vesicle

Identifiers

PMID30231589
PMCPMC6165150
OpenAlexW2890155540

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.