Evidence map›Paper›PMID 30231515›Full record

ReviewViruses2018

Interferon-Mediated Response to Human Metapneumovirus Infection.

Ifeanyi K Uche, Antonieta Guerrero-Plata

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Beyond respiratory syncytial virus and rhinovirus: The other viral respiratory bandits.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2025
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ifeanyi K UcheDepartment of Pathobiological Sciences, Louisiana State University, Baton Rouge, LA 70803, USA. iuche1@lsu.edu.
Antonieta Guerrero-PlataDepartment of Pathobiological Sciences, Louisiana State University, Baton Rouge, LA 70803, USA. aguerrp@lsu.edu.ORCID 0000-0002-0424-2563
Louisiana State University · US

Funding

Flight Attendant Medical Research Institute CIA-140082
6 · The paper itself

Abstract

Human metapneumovirus (HMPV) is one of the leading causes of respiratory diseases in infants and children worldwide. Although this pathogen infects mainly young children, elderly and immunocompromised people can be also seriously affected. To date, there is no commercial vaccine available against it. Upon HMPV infection, the host innate arm of defense produces interferons (IFNs), which are critical for limiting HMPV replication. In this review, we offer an updated landscape of the HMPV mediated-IFN response in different models as well as some of the defense tactics employed by the virus to circumvent IFN response.

Indexed as

Host-Pathogen InteractionsAnimalsDisease Models, AnimalGene Expression Regulation, ViralGenome, ViralGenomicsHumansInterferonsMetapneumovirusParamyxoviridae InfectionsVirus ReplicationInterferonsHMPVhuman metapneumovirusIFNinterferonpneumovirusrespiratory

Identifiers

PMID30231515
PMCPMC6163993
OpenAlexW2892082628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.