ArticleSensors (Basel, Switzerland)2018
Evaluation of Metal Oxide Surface Catalysts for the Electrochemical Activation of Amino Acids.
Article in Sensors (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 21 citations in OpenAlex.
- Polymer thin film-embedded metal oxide-modified electrochemical paper-based sensor for glycine detection.RSC advances · 2025Article
- Sensor technologies for quality control in engineered tissue manufacturing.Biofabrication · 2022Review
- The emergence of psychoanalytical electrochemistry: the translation of MDD biomarker discovery to diagnosis with electrochemical sensing.Translational psychiatry · 2022Review
- Perspective on Nanofiber Electrochemical Sensors: Design of Relative Selectivity Experiments.Polymers · 2021Review
- Elucidating the Electrochemical Mechanism of NG-Hydroxy-L-arginine.Journal of the Electrochemical Society · 2020Article
- Reorientation of Polymers in an Applied Electric Field for Electrochemical Sensors.Journal of the Electrochemical Society · 2020Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Electrochemical detection of amino acids is important due to their correlation with certain diseases; however, most amino acids require a catalyst to electrochemically activate. One common catalyst for electrochemical detection of amino acids are metal oxides. Metal oxide nanoparticles were electrodeposited onto glassy carbon and platinum working electrodes. Cyclic voltammetry (CV) experiments in a flow cell were performed to evaluate the sensors' ability to detect arginine, alanine, serine, and valine at micromolar and nanomolar concentrations as high as 4 mM. Solutions were prepared in phosphate buffer saline (PBS) and then 100 mM NaOH. Specifically, NiO surfaces were responsive to amino acids but variable, especially when exposed to arginine. Polarization resistance experiments and scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDS) data indicated that arginine accelerated the corrosion of the NiO catalyst through the formation of a Schiff base complex.
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Registered trials
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