ArticlePLoS neglected tropical diseases2018
Improved methods to capture the total societal benefits of zoonotic disease control: Demonstrating the cost-effectiveness of an integrated control programme for Taenia solium, soil transmitted helminths and classical swine fever in northern Lao PDR.
Article in PLoS neglected tropical diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- The dual burden of animal and human zoonoses: A systematic review.PLoS neglected tropical diseases · 2022Pooled it
- How can we better integrate the prevention, treatment, control and elimination of neglected tropical diseases with other health interventions? A systematic review.BMJ global health · 2021Pooled it
- A qualitative assessment of the context and enabling environment for the control of Taenia solium infections in endemic settings.PLoS neglected tropical diseases · 2021Pooled it
- Cost-effectiveness of soil-transmitted helminthiasis intervention programmes: A scoping review.PLoS neglected tropical diseases · 2026Article
- A framework for quantifying the multisectoral burden of animal disease to support decision making.Frontiers in veterinary science · 2025Review
- Current evidence of the economic value of One Health initiatives: A systematic literature review.One health (Amsterdam, Netherlands) · 2024Review
- Where exactly do the social and behavioural sciences fit in One Health?Frontiers in public health · 2024Article
- Insights into the diagnosis, vaccines, and control of Taenia solium, a zoonotic, neglected parasite.Parasites & vectors · 2023Review
- A Spatial Autocorrelation Method forTropical medicine and infectious disease · 2023Article
- Approaches for disease prioritization and decision-making in animal health, 2000-2021: a structured scoping review.Frontiers in veterinary science · 2023Article
- A scoping review of burden of disease studies estimating disability-adjusted life years due to Taenia solium.PLoS neglected tropical diseases · 2022Article
- Seroprevalence and Associated Risk Factors of Trichinellosis andTropical medicine and infectious disease · 2022Article
- Maximising Societal Benefit From the Control of Neglected Zoonoses: Identifying Synergies and Trade-Offs in the Control ofFrontiers in veterinary science · 2021Review
- Controlling Tsetse Flies and Ticks Using Insecticide Treatment of Cattle in Tororo District Uganda: Cost Benefit Analysis.Frontiers in veterinary science · 2021Article
- Assessing the burden and spatial distribution of Taenia solium human neurocysticercosis in Ecuador (2013-2017).PLoS neglected tropical diseases · 2020Article
- Modelling forBulletin of the World Health Organization · 2020Article
- Review
- The World Health Organization 2030 goals forGates open research · 2019Article
- Control ofFrontiers in veterinary science · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundControl and elimination of zoonotic diseases requires robust information about their effect on both human and livestock health in order to enable policy formulation and the allocation of resources. This study aimed to evaluate the cost-effectiveness of controlling Taenia solium taeniasis/cysticercosis in both humans and pigs, and soil-transmitted helminths (STH) in humans by integrating their control to on-going human and animal health control programmes in northern Lao People's Democratic Republic.
methodA cross-sectional study was carried out in 49 households, focusing on the prevalence of T. solium taenias/cysticercosis and soil transmitted helminths before and after a twelve month intervention. The village data was collected using a semi-structured questionnaire through a door-to-door survey. The village data was then projected to the wider northern Lao PDR population using stochastic modelling and cost-effectiveness ratio (after aggregating the net cost to capture both human and animal health parameters) and GDP per capita as a threshold, to determine the cost-effectiveness of the integrated control of T. solium taeniasis/ cysticercosis and STH, assuming linear scaling out of the intervention. The zoonotic DALY (zDALY) approach was also used as an alternative method of estimating the cost-effectiveness ratio of controlling T. solium taeniasis/cysticercosis in humans and pigs.
findingsUsing cost-effectiveness analysis after aggregating the net cost and control of T. solium taeniasis/cysticercosis alone as the base case, the study found that simultaneous control of T. solium taeniasis/cysticercosis in humans and pigs, STH in humans and Classical Swine Fever (CSF) in pigs was USD 14 per DALY averted and USD 234 per zDALY averted using zDALY method hence considered highly cost-effective whereas controlling T. solium taeniasis/cysticercosis without incorporating STH and CSF was the least cost-effective (USD 3,672 per DALY averted). Additionally, the cost-effectiveness of controlling T. solium taeniasis/cysticercosis in people and pigs using zDALY as an alternative method was USD 3,662 per zDALY averted which was quite close to our findings using the aggregate net cost method.
conclusionThe study showed that control of T. solium taeniasis/cysticercosis alone in humans and pigs is not cost-effective in northern Lao PDR whereas control of STH is. Consequently, integrating T. solium taeniasis/cysticercosis control with other cost-effective programmes such as STH and CSF markedly improved the cost-effectiveness of the intervention. This is especially important in low resource countries where control of zoonotic neglected tropical diseases could be integrated with the human and animal health sectors to optimize use of the limited resources.
trial registrationAustralia New Zealand Clinical Trials Registry (ANZCTR) ACTRN12614001067662.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.