Evidence map›Paper›PMID 30231027›Full record

ArticlePloS one2018

Perspective of elderly patients on chronic use of potentially inappropriate medication - Results of the qualitative CIM-TRIAD study.

Kathrin Heser, Nadine Janis Pohontsch, Martin Scherer, Antje Löffler, Tobias Luck, Steffi G Riedel-Heller, Wolfgang Maier, Debora Parker, Britta Haenisch, Frank Jessen

Abstract readMulticenter Study
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kathrin HeserDepartment for Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn, Germany.ORCID 0000-0002-9738-2572
Nadine Janis PohontschDepartment of General Practice / Primary Care, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Martin SchererDepartment of General Practice / Primary Care, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Antje LöfflerInstitute of Social Medicine, Occupational Health and Public Health (ISAP), University of Leipzig, Leipzig, Germany.
Tobias LuckDepartment of Economic and Social Sciences & Institute of Social Medicine, Rehabilitation Sciences and Healthcare Research (ISRV), University of Applied Sciences Nordhausen, Nordhausen, Germany.
Steffi G Riedel-HellerInstitute of Social Medicine, Occupational Health and Public Health (ISAP), University of Leipzig, Leipzig, Germany.
Wolfgang MaierDepartment for Neurodegenerative Diseases and Geriatric Psychiatry, University of Bonn, Bonn, Germany.
Debora ParkerGerman Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Britta HaenischGerman Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Frank JessenGerman Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although potentially inappropriate medication (PIM) is associated with risk of harm due to adverse effects, it is frequently prescribed for elderly patients. The aim of this qualitative multi-center study was to gain insight into contextual factors that might lead to chronic PIM use. We conducted semi-structured interviews with elderly patients with or without chronic PIM use (patient interviews: n = 52). Patients were between 86 and 96 years old. The participants were recruited from the AgeCoDe study. Interviews were audiotaped and transcribed verbatim. The transcripts of the interviews were analysed using qualitative content analysis. Deductive and inductive categories were determined. We found contextual factors related to the patient and related to patient-general practitioner (GP) communication that might lead to chronic PIM use (i.e., positive features of PIM, maintaining characteristics of medication intake, barriers to deprescribe PIM, external actors supporting PIM intake, system-related factors). Besides certain health-related behaviours (e.g., own obligation to report to GP) and medication-related attitudes and knowledge (e.g., awareness of side effects and interaction of medicines), patient-GP-interactions that were characterised by mutual agreements on drugs (e.g., concerning dosage or discontinuation of a drug) might be advantageous to reduce the probability of chronic PIM use. The results might assist in the development of guidelines and educational programs aiming to reduce PIM use in the elderly.

Indexed as

Qualitative ResearchAgedAged, 80 and overDrug-Related Side Effects and Adverse ReactionsFemaleGeneral PractitionersHumansInappropriate PrescribingInterviews as TopicMalePatientsPotentially Inappropriate Medication ListRisk AssessmentRisk Factors

Identifiers

PMID30231027
PMCPMC6145513

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.