Evidence map›Paper›PMID 30230444›Full record

ArticleParasite (Paris, France)2018

Comparison of three commercial multiplex PCR assays for the diagnosis of intestinal protozoa.

Brice Autier, Sorya Belaz, Romy Razakandrainibe, Jean-Pierre Gangneux, Florence Robert-Gangneux

Open access · goldAbstract readComparative Study
In one paragraph

Article in Parasite (Paris, France), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 49 citations in OpenAlex.

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  13. Comparative Performance of Eight PCR Methods to DetectPathogens (Basel, Switzerland) · 2021
    Article
  14. High Diversity ofPathogens (Basel, Switzerland) · 2021
    Article
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  18. Evaluation of the AllplexMicroorganisms · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Brice AutierLaboratoire de Parasitologie-Mycologie, Centre Hospitalier Universitaire de Rennes, 2 rue Henri Le Guilloux, 35033, Rennes, France.
Sorya BelazLaboratoire de Parasitologie-Mycologie, Centre Hospitalier Universitaire de Rennes, 2 rue Henri Le Guilloux, 35033, Rennes, France.
Romy RazakandrainibeLaboratoire de Parasitologie-Mycologie, CNR Laboratoire expert Cryptosporidiose, Centre Hospitalier Universitaire de Rouen, Rouen, France.
Jean-Pierre GangneuxLaboratoire de Parasitologie-Mycologie, Centre Hospitalier Universitaire de Rennes, 2 rue Henri Le Guilloux, 35033, Rennes, France.
Florence Robert-GangneuxLaboratoire de Parasitologie-Mycologie, Centre Hospitalier Universitaire de Rennes, 2 rue Henri Le Guilloux, 35033, Rennes, France.
Centre Hospitalier Universitaire de Rennes · FRInstitut de Recherche en Santé, Environnement et Travail · FRUniversité de Reims Champagne-Ardenne · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although microscopic examination of stool samples remains the reference method for the diagnosis of intestinal protozoal infections, these techniques are time-consuming and require operators who are experienced and well trained. Molecular biology seems to offer performances at least equivalent in terms of sensitivity and specificity for certain parasites. This study aimed to compare three multiplex PCR assays on 93 prospectively collected positive stools (prospective cohort) and a panel of 12 more Cryptosporidium-positive samples (Cryptosporidium panel). On the prospective cohort, the sensitivity was 89%, 64% and 41% for Giardia sp. detection for BD Max

Indexed as

Biological AssayCryptosporidiosisCryptosporidiumCryptosporidium parvumEntamoeba histolyticaEntamoebiasisFecesGiardia lambliaGiardiasisHumansIntestinal Diseases, ParasiticIntestinesMolecular Diagnostic TechniquesMultiplex Polymerase Chain ReactionProspective StudiesProtozoan InfectionsReagent Kits, Diagnostic

Identifiers

PMID30230444
PMCPMC6144649
OpenAlexW2892320365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.