Evidence map›Paper›PMID 30230404›Full record

ArticleThe world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry2020

Impaired copper transport in schizophrenia results in a copper-deficient brain state: A new side to the dysbindin story.

Kirsten E Schoonover, Stacy L Queern, Suzanne E Lapi, Rosalinda C Roberts

Open access · greenAbstract read
In one paragraph

Article in The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. The Potential of Hair Matrix for Biomarker Analysis in Schizophrenia.International journal of molecular sciences · 2025
    Review
  3. A primer on copper biology in the brain.Neurobiology of disease · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kirsten E SchoonoverDepartment of Psychology and Behavioral Neuroscience, University of Alabama at Birmingham, Birmingham, AL, USA.
Stacy L QueernDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Suzanne E LapiDepartment of Radiology, University of Alabama at Birmingham, Birmingham, AL, USA.
Rosalinda C RobertsDepartment of Psychiatry and Behavioral Neurobiology, University of Alabama at Birmingham, Birmingham, AL, USA.
University of Alabama at Birmingham · USWashington University in St. Louis · US

Funding

White matter pathology in postmortem schizophrenia brainR21MH108867 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ROBERTS, ROSALINDA C · 2016 to 2017
$404k
Mechanisms of copper dysregulation in schizophreniaR21MH117434 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ROBERTS, ROSALINDA C · 2018 to 2019
$400k
Pyramidal neuron hypoactivity in schizophrenia cortexK00MH122943 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SCHOONOVER, KIRSTEN · 2019 to 2022
$339k
Mechanisms of Dysbindin Abnormalities in SchizophreniaF99NS105208 · NINDS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SCHOONOVER, KIRSTEN · 2017 to 2018
$71k
NIMH NIH HHS K00 MH122943NIMH NIH HHS R21 MH108867NIMH NIH HHS R21 MH117434NINDS NIH HHS F99 NS105208
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BrainCase-Control StudiesCopperCopper Transporter 1Copper-Transporting ATPasesDysbindinHumansMass SpectrometrySchizophreniaSubstantia NigraATP7A protein, humanCopperCopper Transporter 1Copper-Transporting ATPasesDTNBP1 protein, humanDysbindinSLC31A1 protein, humancopperdysbindinpost-mortemSchizophreniasubstantia nigra

Identifiers

PMID30230404
PMCPMC6424639
OpenAlexW2892357226

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.