ArticleJournal of the American Chemical Society2018
Thionoesters: A Native Chemical Ligation-Inspired Approach to Cysteine-Triggered H
Article in Journal of the American Chemical Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 64 citations in OpenAlex.
- Methyl chlorothioformate as a convenient reagent for thionoester synthesis.RSC advances · 2025Article
- NaHS@Cy5@MS@SP nanoparticles improve rheumatoid arthritis by inactivating the Hedgehog signaling pathway through sustained and targeted release of HJournal of nanobiotechnology · 2025Article
- Facile engineering of interactive double network hydrogels for heart valve regeneration.Nature communications · 2024Article
- Discovery of novel β-elemene hybrids with hydrogen sulfide-releasing moiety possessing cardiovascular protective activity for the treatment of atherosclerosis.RSC medicinal chemistry · 2024Article
- A fluorogenic ROS-triggered hydrogen sulfide donor for alleviating cerebral ischemia-reperfusion injury.Theranostics · 2024Article
- Silver Nanoparticle Sensor Array-Based Meat Freshness Inspection System.Foods (Basel, Switzerland) · 2023Article
- C-H⋯S hydrogen bonding interactions.Chemical Society reviews · 2022Review
- A Dinuclear Persulfide-Bridged Ruthenium Compound is a Hypoxia-Selective Hydrogen Sulfide (HAngewandte Chemie (International ed. in English) · 2021Article
- Activatable Small-Molecule Hydrogen Sulfide Donors.Antioxidants & redox signaling · 2020Review
- Cyclic Sulfenyl Thiocarbamates Release Carbonyl Sulfide and Hydrogen Sulfide Independently in Thiol-Promoted Pathways.Journal of the American Chemical Society · 2019Article
- Data-Driven Identification of Hydrogen Sulfide Scavengers.Angewandte Chemie (International ed. in English) · 2019Article
- Dithioesters: simple, tunable, cysteine-selective HChemical science · 2019Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Native chemical ligation (NCL) is a simple, widely used, and powerful synthetic tool to ligate N-terminal cysteine residues and C-terminal α-thioesters via a thermodynamically stable amide bond. Building on this well-established reactivity, as well as advancing our interests in the chemical biology of reactive sulfur species including hydrogen sulfide (H
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.