Evidence map›Paper›PMID 30230190›Full record

SynthesisBJOG : an international journal of obstetrics and gynaecology2019

Associations between maternal physical activity in early and late pregnancy and offspring birth size: remote federated individual level meta-analysis from eight cohort studies.

S Pastorino, T Bishop, S R Crozier, C Granström, K Kordas, L K Küpers, E C O'Brien, K Polanska, K A Sauder, M H Zafarmand and 19 more

Abstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BJOG : an international journal of obstetrics and gynaecology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 7 syntheses or guidelines pooled it.

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  3. Physical Activity during Pregnancy and Newborn Body Composition: A Systematic Review.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

29 authors.

S PastorinoMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
T BishopMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
S R CrozierMRC Lifecourse Epidemiology Unit (University of Southampton), Southampton General Hospital, Southampton, UK.
C GranströmDepartment of Epidemiology Research, Centre for Fetal Programming, State Serum Institute, Copenhagen, Denmark.
K KordasEpidemiology and Environmental Health, School of Public Health and Health Professions, University at Buffalo, Buffalo, NY, USA.
L K KüpersDepartment of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
E C O'BrienObstetrics & Gynaecology, UCD Perinatal Research Centre, School of Medicine, University College Dublin, National Maternity Hospital, Dublin, Ireland.
K PolanskaDepartment of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Lodz, Poland.
K A SauderDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA.
M H ZafarmandDepartment of Public Health, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
R C WilsonInstitute of Health and Society, Newcastle University, Newcastle, UK.
C AgyemangDepartment of Public Health, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
P R BurtonInstitute of Health and Society, Newcastle University, Newcastle, UK.
C CooperMRC Lifecourse Epidemiology Unit (University of Southampton), Southampton General Hospital, Southampton, UK.
E CorpeleijnDepartment of Epidemiology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
D DabeleaDepartment of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Denver, CO, USA.
W HankeDepartment of Environmental Epidemiology, Nofer Institute of Occupational Medicine, Lodz, Poland.
H M InskipMRC Lifecourse Epidemiology Unit (University of Southampton), Southampton General Hospital, Southampton, UK.
F M McAuliffeObstetrics & Gynaecology, UCD Perinatal Research Centre, School of Medicine, University College Dublin, National Maternity Hospital, Dublin, Ireland.
S F OlsenDepartment of Epidemiology Research, Centre for Fetal Programming, State Serum Institute, Copenhagen, Denmark.
T G VrijkotteDepartment of Public Health, Amsterdam Public Health Research Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands.
S BrageMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
A Kennedy3U Diabetes Consortium and School of Health and Human Performance, Dublin City University, Dublin, Ireland.
D O'GormanNIHR Southampton Biomedical Research Centre, University Hospital Southampton NHS Foundation Trust and University of Southampton, Southampton, UK.
P SchererMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
K WijndaeleMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
N J WarehamMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
G DesoyeDepartment of Obstetrics & Gynaecology, Medical University of Graz, Graz, Austria.
K K OngMRC Epidemiology Unit, University of Cambridge, Cambridge, UK.

Funding

Exploring the Fuel-Mediated Programming of Neonatal GrowthR01DK076648 · NIDDK · UNIVERSITY OF COLORADO DENVER/HSC DENVER · PI DABELEA, DANA · 2009 to 2018
$7.0M
Multidisciplinary Clinical and Translational Science (MCTS) Program (TL1)TL1TR000108 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LLOYD-JONES, DONALD M · 2012 to 2013
$59k
Department of Health 10/33/04Medical Research Council G0400491Medical Research Council G0601019Medical Research Council G9815508Medical Research Council MC_U147585819Medical Research Council MC_U147585824Medical Research Council MC_U147585827Medical Research Council MC_UP_A620_1014Medical Research Council MC_UP_A620_1015Medical Research Council MC_UP_A620_1017Medical Research Council MC_UU_12011/1Medical Research Council MC_UU_12011/2Medical Research Council MC_UU_12011/4Medical Research Council MC_UU_12015/1Medical Research Council MC_UU_12015/2Medical Research Council MC_UU_12015/3Medical Research Council MR/K006525/1Medical Research Council MR/K007017/1NCATS NIH HHS TL1 TR000108NIDDK NIH HHS R01 DK076648NIH HHS R01DK076645NIH HHS UL1TR00108Wellcome Trust
6 · The paper itself

Abstract

objectiveEvidence on the impact of leisure time physical activity (LTPA) in pregnancy on birth size is inconsistent. We aimed to examine the association between LTPA during early and late pregnancy and newborn anthropometric outcomes.

designIndividual level meta-analysis, which reduces heterogeneity across studies.

settingA consortium of eight population-based studies (seven European and one US) comprising 72 694 participants.

methodsGeneralised linear models with consistent inclusion of confounders (gestational age, sex, parity, maternal age, education, ethnicity, BMI, smoking, and alcohol intake) were used to test associations between self-reported LTPA at either early (8-18 weeks gestation) or late pregnancy (30+ weeks) and the outcomes. Results were pooled using random effects meta-analyses.

main outcome measuresBirth weight, large-for-gestational age (LGA), macrosomia, small-for-gestational age (SGA), % body fat, and ponderal index at birth.

resultsLate, but not early, gestation maternal moderate to vigorous physical activity (MVPA), vigorous activity, and LTPA energy expenditure were modestly inversely associated with BW, LGA, macrosomia, and ponderal index, without heterogeneity (all: I

conclusionsPhysical activity in late, but not early, pregnancy is consistently associated with modestly lower risk of LGA and macrosomia, but not SGA. TWEETABLE ABSTRACT: In an individual participant meta-analysis, late pregnancy moderate to vigorous physical activity modestly reduced birth size outcomes.

Indexed as

Birth WeightExerciseInfant, Small for Gestational AgeAdipose TissueAdultCohort StudiesDiabetes, GestationalEnergy MetabolismFemaleFetal MacrosomiaHumansInfant, NewbornLinear ModelsObesityOverweightPregnancyBirth weightlarge-for-gestational agemacrosomiaphysical activitypregnancysmall-for-gestational age

Identifiers

PMID30230190
PMCPMC6330060

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.