ReviewChemistry (Weinheim an der Bergstrasse, Germany)2019
A Universal Geochemical Scenario for Formamide Condensation and Prebiotic Chemistry.
Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 70 citations in OpenAlex.
- Experimental and Computational Simulation of the Prebiotic Peptide Bond Formation Driven by Wet-Dry Cycles and Gamma Ionizing Radiation: An Insight into Molecular Evolution.Journal of molecular evolution · 2026Article
- In Situ, Real-Time Imaging of pH Gradients and Solution Flows through Silica Garden Membranes during Tube Growth.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Origin of the RNA World in Cold Hadean Geothermal Fields Enriched in Zinc and Potassium: Abiogenesis as a Positive Fallout from the Moon-Forming Impact?Life (Basel, Switzerland) · 2025Article
- The protometabolic nature of prebiotic chemistry.Chemical Society reviews · 2023Review
- On the Role ofLife (Basel, Switzerland) · 2022Article
- The role of borosilicate glass in Miller-Urey experiment.Scientific reports · 2021Article
- Synthesis of lipid membranes for artificial cells.Nature reviews. Chemistry · 2021Review
- Coenzymes and Their Role in the Evolution of Life.Angewandte Chemie (International ed. in English) · 2021Review
- Prebiotic Organic Chemistry of Formamide and the Origin of Life in Planetary Conditions: What We Know and What Is the Future.International journal of molecular sciences · 2021Review
- Prebiotic Nucleoside Synthesis: The Selectivity of Simplicity.Chemistry (Weinheim an der Bergstrasse, Germany) · 2020Review
- A Universal Geochemical Scenario for Formamide Condensation and Prebiotic Chemistry.Chemistry (Weinheim an der Bergstrasse, Germany) · 2019Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The condensation of formamide has been shown to be a robust chemical pathway affording molecules necessary for the origin of life. It has been experimentally demonstrated that condensation reactions of formamide are catalyzed by a number of minerals, including silicates, phosphates, sulfides, zirconia, and borates, and by cosmic dusts and meteorites. However, a critical discussion of the catalytic power of the tested minerals, and the geochemical conditions under which the condensation would occur, is still missing. We show here that mineral self-assembled structures forming under alkaline silica-rich solutions are excellent catalysts for the condensation of formamide with respect to other minerals. We also propose that these structures were likely forming as early as 4.4 billion years ago when the whole earth surface was a reactor, a global scale factory, releasing large amounts of organic compounds. Our experimental results suggest that the conditions required for the synthesis of the molecular bricks from which life self-assembles, rather than being local and bizarre, appears to be universal and geologically rather conventional.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.