Evidence map›Paper›PMID 30230036›Full record

Trial reportClinical transplantation2018

Association between the "Timed Up and Go Test" at transplant evaluation and outcomes after kidney transplantation.

Ariane T Michelson, Demetra S Tsapepas, S Ali Husain, Corey Brennan, Mariana C Chiles, Brian Runge, Jennifer Lione, Byum H Kil, David J Cohen, Lloyd E Ratner and 1 more

Abstract readClinical Trial
In one paragraph

Trial report in Clinical transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. An overview of frailty in kidney transplantation: measurement, management and future considerations.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020
    Review
  8. Article
  9. Article
  10. Frailty and Long-Term Post-Kidney Transplant Outcomes.Current transplantation reports · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ariane T MichelsonDepartment of Medicine, Division of Nephrology, Columbia University Medical Center, New York, New York.ORCID 0000-0002-2667-5044
Demetra S TsapepasThe Columbia University Renal Epidemiology (CURE) Group, New York, New York.
S Ali HusainDepartment of Medicine, Division of Nephrology, Columbia University Medical Center, New York, New York.
Corey BrennanDepartment of Medicine, Division of Nephrology, Columbia University Medical Center, New York, New York.
Mariana C ChilesDepartment of Medicine, Division of Nephrology, Columbia University Medical Center, New York, New York.
Brian RungeDepartment of Surgery, Division of Transplantation, Columbia University Medical Center, New York, New York.
Jennifer LioneDepartment of Medicine, Division of Nephrology, Columbia University Medical Center, New York, New York.
Byum H KilDepartment of Medicine, Division of Nephrology, Columbia University Medical Center, New York, New York.
David J CohenDepartment of Medicine, Division of Nephrology, Columbia University Medical Center, New York, New York.
Lloyd E RatnerDepartment of Surgery, Division of Transplantation, Columbia University Medical Center, New York, New York.
Sumit MohanDepartment of Medicine, Division of Nephrology, Columbia University Medical Center, New York, New York.ORCID 0000-0002-5305-9685

Funding

5/14 APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO) Clinical CenterU01DK116066 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Sumit Mohan, Deirdre Sawinski · 2017 to 2026
$2.5M
Increasing Minority Population Awareness through Community Teaching for Improved Organ Donation (IMPACT for Improved Organ Donation)R01DK114893 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MOHAN, SUMIT · 2017 to 2021
$1.2M
NIDDK NIH HHS R01 DK114893NIDDK NIH HHS U01 DK116066
6 · The paper itself

Abstract

backgroundStudies have demonstrated the Timed Up and Go Test's (TUGT) ability to forecast postoperative outcomes for several surgical specialties. Evaluations of the TUGT for waitlist and posttransplant outcomes have yet to be examined in kidney transplantation.

objectiveTo assess the prognostic utility of the TUGT and its associations with waitlist and posttransplant outcomes for kidney transplant candidates. DESIGN AND

methodsSingle-center, prospective study of 518 patients who performed TUGT during their transplant evaluation between 9/1/2013-11/30/2014. TUGT times were evaluated as a continuous variable or 3-level discrete categorical variable with TUGT times categorized as long (>9 seconds), average (8-9 seconds), or short (5-8 seconds).

resultsTransplanted individuals had shorter TUGT times than those who remained on the waitlist (8.99 vs 9.79 seconds, P < 0.001). Bivariable and multivariable logistic regression showed that after adjusting for age, there was no association between TUGT times and probability of waitlist removal (OR 0.997 [0.814-1.221]), prolonged length of stay posttransplant (OR 1.113 [0.958-1.306] for deceased donor, OR 0.983 [0.757-1.277] for living donor), and 30-day readmissions (OR 0.984 [0.845-1.146] for deceased donor, OR 1.254 [0.976-1.613] for living donor).

conclusionsThe TUGT was not associated with waitlist removal or prolonged hospitalization for kidney transplant candidates. Alternative assessments of global health, such as functional status or frailty, should be considered for evaluation of potential kidney transplant candidates.

Indexed as

Graft SurvivalTissue DonorsAdolescentAdultFemaleFollow-Up StudiesGlomerular Filtration RateGraft RejectionHospitalizationHumansKidney Failure, ChronicKidney Function TestsKidney TransplantationMaleMiddle AgedPostoperative Complicationskidney transplantationpatient characteristicsrisk stratificationtransplant evaluationwaitlisting

Identifiers

PMID30230036
PMCPMC6265056

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.