Evidence map›Paper›PMID 30229560›Full record

ArticleMagnetic resonance in medicine2019

Wideband myocardial perfusion pulse sequence for imaging patients with a cardiac implantable electronic device.

KyungPyo Hong, Jeremy D Collins, Bradley P Knight, James C Carr, Daniel C Lee, Daniel Kim

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Myocardial blood flow quantification in patients with an implanted cardiodefibrillator during stress and at rest using a wideband perfusion pulse sequence: an initial feasibility study.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Clinical experience regarding safety and diagnostic value of cardiovascular magnetic resonance in patients with a subcutaneous implanted cardioverter/defibrillator (S-ICD) at 1.5 T.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2020
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

KyungPyo HongDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL.ORCID 0000-0001-8323-4555
Jeremy D CollinsDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL.
Bradley P KnightDivision of Cardiology, Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL.
James C CarrDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL.
Daniel C LeeDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL.
Daniel KimDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL.

Funding

Precision MRI of Left Atrial Fibrosis for Patients with Atrial FibrillationR01HL116895 · NHLBI · UNIVERSITY OF UTAH · PI KIM, DANIEL · 2014 to 2025
$5.1M
Rapid Real-Time Cardiovascular MRI for Detecting Coronary Artery DiseaseR01HL138578 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DANIEL, LEE, DANIEL CHING-HAO · 2017 to 2019
$1.1M
Rapid Pediatric Cardiovascular MRI without Contrast Agent or AnesthesiaR21EB024315 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DANIEL · 2017 to 2018
$567k
MRI of Left Atrial Hemodynamic Disorders in Atrial FibrillationR21AG055954 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DANIEL, MARKL, MICHAEL · 2017 to 2018
$487k
NHLBI NIH HHS R01 HL116895NHLBI NIH HHS R01HL116895NHLBI NIH HHS R01 HL138578NHLBI NIH HHS R01HL138578NIA NIH HHS R21 AG055954NIA NIH HHS R21AG055954NIBIB NIH HHS R21 EB024315NIBIB NIH HHS R21EB024315NIH HHSNIH HHS R01HL116895NIH HHS R01HL138578NIH HHS R21AG055954NIH HHS R21EB024315
6 · The paper itself

Abstract

purposeTo develop a wideband cardiac perfusion pulse sequence and test whether it is capable of suppressing image artifacts in patients with a cardiac implantable electronic device (CIED), while not exceeding the specific absorption rate (SAR) limit (2.0 W/kg).

methodsA wideband perfusion pulse sequence was developed by incorporating a wideband saturation pulse to achieve a good balance between saturation of magnetization and SAR. Clinical standard and wideband perfusion MRI scans were performed back-to-back in a randomized order on 16 patients with a CIED undergoing clinical cardiac MRI. Two expert readers graded the artifact intensity and extent on a segmental basis using a 5-point Likert scale, where significant artifact was defined by a composite score. The variance in myocardial signal prior to tissue-enhancement was analyzed to quantify artifact-intensity. Whole-body SAR values computed by the MR scanner were read from the DICOM header. Either a paired t-test or Wilcoxon signed-rank test was performed to compare two groups.

resultsWhile the mean whole-body SAR for a single-slice wideband perfusion scan (0.38 ± 0.08W/kg) was significantly (p < 0.05) higher than for a single-slice standard perfusion scan (0.11 ± 0.03W/kg), it was 81% below 2.0 W/kg. The mean variance in myocardial signal prior to tissue-enhancement was significantly (p < 0.001) higher for standard (422.6 ± 306.6 a.u.) than wideband (107.0 ± 60.9 a.u.). Among 105 myocardial segments, standard produced 19 segments (18%) that were deemed to have significant artifacts, whereas wideband produced only 3 segments (3%).

conclusionA wideband perfusion pulse sequence is capable of suppressing image artifacts induced by a CIED while not exceeding SAR at 2.0 W/kg.

Indexed as

Defibrillators, ImplantableMagnetic Resonance ImagingMyocardial Perfusion ImagingAdolescentAdultAgedArtifactsContrast MediaFemaleHeartHumansImage EnhancementMaleMiddle AgedMyocardiumPhantoms, ImagingContrast Media

Identifiers

PMID30229560
PMCPMC6289847

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.