Evidence map›Paper›PMID 30229453›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2018

Adherence to ATA 2015 guidelines in the management of unifocal non-invasive papillary thyroid cancer: a clinical survey among endocrinologists and surgeons.

Karen Or, Carlos Benbassat, Shlomit Koren, Miriam Shteinshneider, Ronit Koren, Dror Cantrell, Esther Kummer, Limor Muallem Kalmovich

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Risk factors of skip lateral lymph node metastasis in papillary thyroid carcinoma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021
    Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Karen OrEndocrine Institute, Assaf Harofeh Center, Tzrifin, Beer Yaakov, 70300, Israel. or.karen@gmail.com.ORCID http://orcid.org/0000-0001-7058-0686
Carlos BenbassatEndocrine Institute, Assaf Harofeh Center, Tzrifin, Beer Yaakov, 70300, Israel.
Shlomit KorenEndocrine Institute, Assaf Harofeh Center, Tzrifin, Beer Yaakov, 70300, Israel.
Miriam ShteinshneiderEndocrine Institute, Assaf Harofeh Center, Tzrifin, Beer Yaakov, 70300, Israel.
Ronit KorenEndocrine Institute, Assaf Harofeh Center, Tzrifin, Beer Yaakov, 70300, Israel.
Dror CantrellEndocrine Institute, Assaf Harofeh Center, Tzrifin, Beer Yaakov, 70300, Israel.
Esther KummerEndocrine Institute, Assaf Harofeh Center, Tzrifin, Beer Yaakov, 70300, Israel.
Limor Muallem KalmovichDepartment of ENT, Assaf Harofeh Medical Center, Tzrifin, Beer Yacov, 73000, Israel.
Tel Aviv University · ILAssaf Harofeh Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite updated guidelines, management of thyroid nodules remains controversial. We aim to check implementation of new guidelines by ear-nose-throat (ENT) surgeons and endocrinologists.

methodsA questionnaire was e-mailed including demographic data and an index case: a healthy 26-year-old women with a 3-cm Bethesda III (B3) atypia of undetermined significance solitary nodule and eventually papillary thyroid cancer (PTC).

resultsRespondent rate was 50.5%, 93 endocrinologists, 55 surgeons. For this case, 77.4% would repeat fine-needle aspiration (FNA), 25.3% order molecular analysis and 22.6% do surgery. If repeated FNA remained B3, 51% would choose surgery, 17.3% molecular analysis and 31.6% follow-up only. If repeated FNA was B6, 58.5% would recommend total (TTx) and 41.5% hemithyroidectomy (HTx). In pathologically confirmed PTC after HTx, 42.4% would recommend completion, 26.8% radioactive iodine (RAI) treatment. For a > = 4-cm tumor, 49.2% would recommend TTx. For a tumor 2-4 cm, 41% would recommend TTx. Variables favoring TTx were family history and radiation exposure. Only 17.4% would prefer TTx when small benign contralateral tumor is present. Reassessment at 1 year with undetectable thyroglobulin (Tg) included stimulated Tg (stTg) (72.5%), neck US only (27.5%) and combined US-stTg (59.4%); only 10.3% would order a diagnostic scan. For recurrence in two (13-9 mm) lymph nodes, 59.3% recommend reoperation, 16.3% RAI and 24.4% active surveillance. There were no major differences between endocrinologists and ENT surgeons.

conclusionsWe report a considerable lack of adherence to new guidelines, with only 50% recommending HTx for a 4-cm unifocal low-risk PTC tumor.

Indexed as

Guideline AdherenceAdultBiopsy, Fine-NeedleEndocrinologyFemaleHumansMaleMiddle AgedNeoplasm StagingPractice Guidelines as TopicPractice Patterns, Physicians'ReoperationSurveys and QuestionnairesThyroglobulinThyroid Cancer, PapillaryThyroidectomyThyroglobulinApproachGuidelinesOncologyPapillary thyroid cancerSurveyThyroid

Identifiers

PMID30229453
OpenAlexW2890343227

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.