ArticlePediatric quality & safety
A Quality Improvement Collaborative for Pediatric Sepsis: Lessons Learned.
Article in Pediatric quality & safety. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Surviving Sepsis Campaign International Guidelines for the Management of Sepsis and Septic Shock in Children 2026.Intensive care medicine · 2026Pooled it
- Early recognition and bundle-based management of pediatric sepsis in the emergency department: a narrative review.Translational pediatrics · 2026Review
- Association between corrected serum calcium levels and 28-day mortality in patients with sepsis: A cohort study.Medicine · 2026Article
- Training for Pediatric Sepsis-A Medical Education Perspective and Potential Role of Artificial Intelligence.Children (Basel, Switzerland) · 2025Review
- Epinephrine vs Norepinephrine as Initial Treatment in Children With Septic Shock.JAMA network open · 2025Article
- Identification of distinct clinical profiles of sepsis risk in paediatric emergency department patients using Bayesian profile regression.BMJ paediatrics open · 2025Article
- Pediatric Sepsis in General Emergency Departments: Association Between Pediatric Sepsis Case Volume, Care Quality, and Outcome.Annals of emergency medicine · 2024Article
- Article
- Utilizing big data from electronic health records in pediatric clinical care.Pediatric research · 2023Review
- "These Are Our Kids": Qualitative Interviews With Clinical Leaders in General Emergency Departments on Motivations, Processes, and Guidelines in Pediatric Sepsis Care.Annals of emergency medicine · 2022Article
- Impact of an electronic alert system for pediatric sepsis screening a tertiary hospital experience.Scientific reports · 2022Article
- Patient and economic impact of implementing a paediatric sepsis pathway in emergency departments in Queensland, Australia.Scientific reports · 2022Article
- Queensland Pediatric Sepsis Breakthrough Collaborative: Multicenter Observational Study to Evaluate the Implementation of a Pediatric Sepsis Pathway Within the Emergency Department.Critical care explorations · 2021Article
- Knowledge translation following the implementation of a state-wide Paediatric Sepsis Pathway in the emergency department- a multi-centre survey study.BMC health services research · 2021Observational
- A pediatric perspective on World Sepsis Day in 2021: leveraging lessons from the pandemic to reduce the global pediatric sepsis burden?American journal of physiology. Lung cellular and molecular physiology · 2021Article
- Metric Development for the Multicenter Improving Pediatric Sepsis Outcomes (IPSO) Collaborative.Pediatrics · 2021Article
- Development and validation of an early warning tool for sepsis and decompensation in children during emergency department triage.Scientific reports · 2021Article
- [Paediatric Life Support].Notfall & rettungsmedizin · 2021Review
- A Pediatric Sepsis Protocol Reduced Mortality and Dysfunctions in a Brazilian Public Hospital.Frontiers in pediatrics · 2021Article
- Development of a Quality Improvement Learning Collaborative to Improve Pediatric Sepsis Outcomes.Pediatrics · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSepsis is a leading cause of morbidity and mortality in children worldwide. Barriers exist for timely recognition and management in emergency care settings. This 1-year quality improvement collaborative sought to reduce mortality from sepsis.
methodsFifteen hospitals participated initially. We included children with a spectrum of illness from sepsis to septic shock. The intervention bundle focused on recognition, escalation of care, and the first hour of resuscitation. We conducted monthly learning sessions and disseminated data reports of site-specific and aggregated metrics to drive rapid cycle improvement.
resultsSeven sites contributed enough data to be analyzed. Of the 1,173 pediatric patients in the total cohort, 506 presented with severe sepsis/septic shock. Quarterly data demonstrated a mean improvement in initial clinical assessment from 46% to 60% (
conclusionsA quality improvement collaborative focused on improving timely recognition and management of pediatric sepsis to septic shock led to some process improvements but did not show improvement in mortality. Future national efforts should standardize definitions and processes of care for sepsis to septic shock, including the identification of a "time zero" for measuring the timeliness of treatment.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.