Evidence map›Paper›PMID 30228894›Full record

ArticleUnited European gastroenterology journal2018

Dietary supplementation of vitamin D prevents the development of western diet-induced metabolic, hepatic and cardiovascular abnormalities in rats.

Giovanna Mazzone, Carmine Morisco, Vincenzo Lembo, Giuseppe D'Argenio, Maria D'Armiento, Antonella Rossi, Carmine Del Giudice, Bruno Trimarco, Nicola Caporaso, Filomena Morisco

Open access · bronzeAbstract read
In one paragraph

Article in United European gastroenterology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Review
  3. Effects of supplementation with vitamin DFrontiers in veterinary science · 2025
    Article
  4. Article
  5. Vitamin D improves hepatic steatosis in NAFLDFrontiers in endocrinology · 2023
    Article
  6. Article
  7. Review
  8. Review
  9. Exercise Training: The Holistic Approach in Cardiovascular Prevention.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021
    Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Insulin Resistance the Hinge Between Hypertension and Type 2 Diabetes.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2020
    Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Giovanna MazzoneGastroenterology, Department of Clinical Medicine and Surgery, University 'Federico II', Naples, Italy.
Carmine MoriscoDepartment of Advanced Biomedical Sciences, University 'Federico II', Naples, Italy.
Vincenzo LemboGastroenterology, Department of Clinical Medicine and Surgery, University 'Federico II', Naples, Italy.
Giuseppe D'ArgenioGastroenterology, Department of Clinical Medicine and Surgery, University 'Federico II', Naples, Italy.ORCID 0000-0002-7217-0960
Maria D'ArmientoDepartment of Advanced Biomedical Sciences, University 'Federico II', Naples, Italy.
Antonella RossiGastroenterology, Department of Clinical Medicine and Surgery, University 'Federico II', Naples, Italy.
Carmine Del GiudiceDepartment of Advanced Biomedical Sciences, University 'Federico II', Naples, Italy.
Bruno TrimarcoDepartment of Advanced Biomedical Sciences, University 'Federico II', Naples, Italy.ORCID 0000-0002-0701-6449
Nicola CaporasoGastroenterology, Department of Clinical Medicine and Surgery, University 'Federico II', Naples, Italy.
Filomena MoriscoGastroenterology, Department of Clinical Medicine and Surgery, University 'Federico II', Naples, Italy.
Federico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe western diet high in fat and fructose may cause metabolic disorders and cardiovascular diseases.

objectiveTo evaluate whether long-term daily vitamin D

methodsThree groups of rats were fed for 6 months with standard diet (SD), western diet (WD) or WD containing 23 IU/day/rat vitamin D

resultsSixty-one per cent of hepatocytes in WD rats had steatotic vacuoles compared with just 27% in rats on a WD plus vitamin D

conclusionIn animal models of liver and cardiovascular metabolic damage, the supplementation of vitamin D

Indexed as

cardiovascular diseaseDiabetesHOMAinsulinvitamin Dwestern diet

Identifiers

PMID30228894
PMCPMC6137584
OpenAlexW2803136531

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.