Evidence map›Paper›PMID 30228855›Full record

ArticleOxidative medicine and cellular longevity2018

Neuroprotective Effects of Polydeoxyribonucleotide in a Murine Model of Cadmium Toxicity.

Herbert R Marini, Domenico Puzzolo, Antonio Micali, Elena Bianca Adamo, Natasha Irrera, Antonina Pisani, Giovanni Pallio, Vincenzo Trichilo, Consuelo Malta, Alessandra Bitto and 3 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Herbert R MariniDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.ORCID 0000-0002-8254-177X
Domenico PuzzoloDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy.ORCID 0000-0002-1651-1409
Antonio MicaliDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy.ORCID 0000-0003-0826-1910
Elena Bianca AdamoDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy.
Natasha IrreraDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.ORCID 0000-0002-1134-7080
Antonina PisaniDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy.
Giovanni PallioDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.ORCID 0000-0002-4187-2265
Vincenzo TrichiloDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Consuelo MaltaDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy.
Alessandra BittoDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.ORCID 0000-0001-9300-7532
Francesco SquadritoDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.ORCID 0000-0002-8868-0762
Domenica AltavillaDepartment of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, Messina, Italy.ORCID 0000-0002-1033-0527
Letteria MinutoliDepartment of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
University of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cadmium (Cd) is a harmful heavy metal, which causes severe brain damage and neurotoxic effects. Polydeoxyribonucleotide (PDRN) stimulates adenosine A

Indexed as

AnimalsBrain-Derived Neurotrophic FactorBrain EdemaCadmiumDisease Models, AnimalGlutathioneHippocampusMaleMalondialdehydeMiceMice, Inbred C57BLNeuronsNeuroprotective AgentsPolydeoxyribonucleotidesReaction TimeTOR Serine-Threonine KinasesBrain-Derived Neurotrophic FactorCadmiumGlutathioneMalondialdehydeNeuroprotective AgentsPolydeoxyribonucleotidesTOR Serine-Threonine Kinases

Identifiers

PMID30228855
PMCPMC6136506
OpenAlexW2888939354

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.