Evidence map›Paper›PMID 30228784›Full record

ArticleWorld journal of gastroenterology2018

Gastroduodenal ulcer bleeding in elderly patients on low dose aspirin therapy.

Koh Fukushi, Keiichi Tominaga, Kazunori Nagashima, Akira Kanamori, Naoya Izawa, Mimari Kanazawa, Takako Sasai, Hideyuki Hiraishi

Open access · hybridAbstract readComparative Study
In one paragraph

Article in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Aspirin Caused Intestinal Damage through FXR and ET-1 Signaling Pathways.International journal of molecular sciences · 2024
    Article
  2. Review
  3. Article
  4. The Synergistic Effects ofDrug design, development and therapy · 2021
    Article
  5. Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Koh FukushiDepartment of Gastroenterology, Dokkyo Medical University, Tochigi 3210293, Japan.
Keiichi TominagaDepartment of Gastroenterology, Dokkyo Medical University, Tochigi 3210293, Japan. tominaga@dokkyomed.ac.jp.
Kazunori NagashimaDepartment of Gastroenterology, Dokkyo Medical University, Tochigi 3210293, Japan.
Akira KanamoriDepartment of Gastroenterology, Dokkyo Medical University, Tochigi 3210293, Japan.
Naoya IzawaDepartment of Gastroenterology, Dokkyo Medical University, Tochigi 3210293, Japan.
Mimari KanazawaDepartment of Gastroenterology, Dokkyo Medical University, Tochigi 3210293, Japan.
Takako SasaiDepartment of General Internal Medicine 2, Kawasaki Medical School General Medical Center, Okayama 700850, Japan.
Hideyuki HiraishiDepartment of Gastroenterology, Dokkyo Medical University, Tochigi 3210293, Japan.
Kawasaki Medical School · JPDokkyo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo determine the clinical characteristics of elderly patients of hemorrhagic gastroduodenal ulcer on low-dose aspirin (LDA) therapy.

methodsA total of 1105 patients with hemorrhagic gastroduodenal ulcer treated in our hospital between January 2000 and March 2016 were grouped by age and drugs used, and these groups were compared in several factors. These groups were compared in terms of length of hospital stay, presence/absence of hemoglobin (Hb) decrease, presence/absence of blood transfusion, Forrest I, percentage of

resultsThe percentage of blood transfusion (62.6%

conclusionA combination of LDA with antithrombotic drugs or non-steroidal anti-inflammatory drugs (NSAIDs) contributes to aggravation. And advanced age is not an aggravating factor when LDA monotherapy is used.

Indexed as

AgedAged, 80 and overAge FactorsAnti-Inflammatory Agents, Non-SteroidalAspirinCerebrovascular DisordersDrug Therapy, CombinationFemaleFibrinolytic AgentsHelicobacter InfectionsHelicobacter pyloriHumansJapanMaleMiddle AgedMyocardial IschemiaAnti-Inflammatory Agents, Non-SteroidalAspirinFibrinolytic AgentsAntithrombotic drugsElderly patientsHemorrhagic gastroduodenal ulcerLow-dose aspirinProton pump inhibitor

Identifiers

PMID30228784
PMCPMC6141337
OpenAlexW2891961820

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.