Evidence map›Paper›PMID 30228782›Full record

ArticleWorld journal of gastroenterology2018

Formin-like 3 regulates RhoC/FAK pathway and actin assembly to promote cell invasion in colorectal carcinoma.

Yuan-Feng Zeng, Yi-Sheng Xiao, Yong Liu, Xiao-Jiang Luo, Li-Dan Wen, Qian Liu, Min Chen

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Role of RhoC in cancer cell migration.Cancer cell international · 2021
    Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. [Effect of honokiol on proliferation, migration and apoptosis of human tongue cancer CAL-27 cellsNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2020
    Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yuan-Feng ZengDepartment of Pathology, Jiangxi Provincial People's Hospital, Nanchang 330006, Jiangxi Province, China. zyf760928@163.com.
Yi-Sheng XiaoTeaching and Researching Section of Morphology, College of Basic Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang 330004, Jiangxi Province, China.
Yong LiuDepartment of Pathology, Jiangxi Provincial People's Hospital, Nanchang 330006, Jiangxi Province, China.
Xiao-Jiang LuoDepartment of General Surgery, Jiangxi Provincial People's Hospital, Nanchang 330006, Jiangxi Province, China.
Li-Dan WenClinical Medical Sciences Institute, Jiangxi Provincial People's Hospital, Nanchang 330006, Jiangxi Province, China.
Qian LiuDepartment of Pathology, Jiangxi Provincial People's Hospital, Nanchang 330006, Jiangxi Province, China.
Min ChenDepartment of Pathology, Jiangxi Provincial People's Hospital, Nanchang 330006, Jiangxi Province, China.
Jiangxi Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo clarify the underlying mechanism of formin-like 3 (FMNL3) in the promotion of colorectal carcinoma (CRC) cell invasion.

methodsThe

resultsThe

conclusionFMNL3 regulates the RhoC/FAK signaling pathway and RhoC-dependent remodeling of actin-based protrusions to promote CRC invasion.

Indexed as

ActinsCell AdhesionCell Line, TumorCell MovementColorectal NeoplasmsEnzyme InhibitorsFocal Adhesion Kinase 2ForminsHEK293 CellsHumansNeoplasm InvasivenessProteinsrhoC GTP-Binding ProteinRNA, Small InterferingSignal TransductionActinsEnzyme InhibitorsFMNL3 protein, humanFocal Adhesion Kinase 2ForminsProteinsPTK2B protein, humanrhoC GTP-Binding ProteinRHOC protein, humanRNA, Small InterferingActin assemblyColorectal carcinomaFormin-like 3InvasionRhoC/FAK pathway

Identifiers

PMID30228782
PMCPMC6141330
OpenAlexW2889918677

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.