Evidence map›Paper›PMID 30228731›Full record

ReviewMissouri medicine

Not Salt But Sugar As Aetiological In Osteoporosis: A Review.

James J DiNicolantonio, Varshil Mehta, Sojib Bin Zaman, James H O'Keefe

Open access · greenAbstract readReview
In one paragraph

Review in Missouri medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Secondary Osteoporosis and Metabolic Bone Diseases.Journal of clinical medicine · 2022
    Review
  14. Article
  15. Article
  16. Idiopathic Osteoporosis and Nephrolithiasis: Two Sides of the Same Coin?International journal of molecular sciences · 2020
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

James J DiNicolantonioJames J. DiNicolantonio, PharmD, is at Saint Luke's Mid America Heart Institute, Kansas City, Mo.
Varshil MehtaVarshil Mehta, MBBS, is with Mount Sinai Hospital, New York and MGM Medical College, Navi Mumbai, India.
Sojib Bin ZamanSojib Bin Zaman, MBBS, is with the International Centre of Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh.
James H O'KeefeJames H. O'Keefe, MD, MSMA member since 2003, is at Saint Luke's Mid America Heart Institute, Kansas City, Mo.
Saint Luke's Hospital · USInternational Centre for Diarrhoeal Disease Research · BDMount Sinai Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salt has notoriously been blamed for causing an increase in the urinary excretion of calcium, and thus is a considered a risk factor for osteoporosis. However, the increase in the urinary excretion of calcium with higher sodium intakes can be offset by the increased intestinal absorption of dietary calcium. Thus, the overall calcium balance does not appear to be reduced with a higher sodium intake. However, the other ubiquitous white crystal, sugar, may lead to osteoporosis by increasing inflammation, hyperinsulinemia, increased renal acid load, reduced calcium intake, and increased urinary calcium excretion. Sugar, not salt, is the more likely white crystal to be a risk factor for osteoporosis when overconsumed.

Indexed as

AgedAged, 80 and overCalciumDietary SugarsFemaleHumansMaleMiddle AgedOsteoporosisSodium, DietaryCalciumDietary SugarsSodium, Dietary

Identifiers

PMID30228731
PMCPMC6140170
OpenAlexW2981841463

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.