ReviewMissouri medicine
Constipation: Evaluation and Management.
Review in Missouri medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05687214 (Investigation on the Effects of an Osteopathic Manipulative Treatment for Constipation in People With Rett Syndrome), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Investigation on the Effects of an Osteopathic Manipulative Treatment for Constipation in People With Rett Syndrome
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- The Effectiveness of Caffeine in Reducing Constipation in Adults: A Systematic Review.International urogynecology journal · 2025Pooled it
- Point-of-care ultrasound diagnostic accuracy for fecal impaction in the emergency department: a prospective study.Internal and emergency medicine · 2026Trial
- Effectiveness of physiotherapy in children with functional constipation.Pediatric surgery international · 2024Trial
- Prebiotic Galacto-Oligosaccharides Impact Stool Frequency and Fecal Microbiota in Self-Reported Constipated Adults: A Randomized Clinical Trial.Nutrients · 2022Trial
- Peripheral non-invasive focused ultrasound alleviates constipation by reducing gastrointestinal inflammation.Experimental physiology · 2026Article
- The laxative efficacy of a mixed extract ofOpen veterinary journal · 2026Article
- Unlocking the colon clock: Bridging the gap in colonic transit time studies for optimal management of chronic constipation.World journal of gastrointestinal pharmacology and therapeutics · 2026Review
- Improving Constipation in Critical Care Patients: A Single-Centre Prospective Cohort Closed-Loop Clinical Audit.Cureus · 2026Article
- Pathophysiological mechanisms, diagnostic innovations, and multimodal therapeutic strategies for slow transit constipation.BMC gastroenterology · 2025Review
- Description of the Characteristics of Sleeve Gastrectomy Patients and the Effect of Bowel Movement on Quality of Life After Sleeve Gastrectomy.Obesity surgery · 2025Article
- Differences in the Effectiveness of Uridine andPharmaceuticals (Basel, Switzerland) · 2025Article
- L-Arabinose Alleviates Functional Constipation in Mice by Regulating Gut Microbiota and Metabolites.Foods (Basel, Switzerland) · 2025Article
- Effects of the Intestinal Status and Clinical Factors of Korean Middle-Aged People Through the Consumption of Functional Foods ContainingClinical nutrition research · 2025Article
- Dietary fiber from burdock root ameliorates functional constipation in aging rats by regulating intestinal motility.Frontiers in nutrition · 2025Article
- Risk factors for constipation during pregnancy: a multicentre prospective cohort study.BMC pregnancy and childbirth · 2024Observational
- Impact of Constipation on Health Outcomes in Medically Hospitalized Patients: A Prospective Study on Laxative Use and Health Care Outcomes.Medicina (Kaunas, Lithuania) · 2024Article
- Review
- Article
- Evaluation of probiotics in the treatment of hypothyroidism in early pregnancy combined with small intestinal bacterial overgrowth.Food science & nutrition · 2024Article
- Effect of laxative polyherbal paste for loperamide induced constipation in rats.American journal of translational research · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Constipation is defined as the infrequent passage of stools or difficulty with evacuation of stools. Constipation can be classified as primary or secondary, and primary constipation can be further divided into slow transit constipation or outlet obstruction. The diagnostic workup involves focused lab tests and structural evaluation, followed by a therapeutic trial of fiber and laxatives, and finally, specialized tests. Treatment can consist of dietary changes, medications, physical therapy, and possibly surgery in refractory cases.
Indexed as
Identifiers
30228729PMC6140151W2987469690What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.