ReviewMissouri medicine
Gastroesophageal Reflux Disease (GERD).
Review in Missouri medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
112 citing papers in PubMed, 7 syntheses or guidelines pooled it, 103 citations in OpenAlex.
- Prevalence and risk factors of gastro-oesophageal reflux disease in Saudi Arabia: a systematic review and meta-analysis.BMJ open · 2026Pooled it
- Effects of Helicobacter pylori infection on gastric cancer, obesity and esophageal diseases: a systematic review and meta-analysis.BMC gastroenterology · 2025Pooled it
- Effectiveness of dietary interventions in managing pediatric gastroesophageal reflux disease: a comprehensive systematic review.European journal of medical research · 2025Pooled it
- The relationship between amino acids and gastroesophageal reflux disease: evidence from a mendelian randomization analysis combined with a meta-analysis.Frontiers in immunology · 2025Pooled it
- Effectiveness of abdominal electroacupuncture therapy for poststroke constipation: a meta-analysis.Frontiers in neurology · 2024Pooled it
- Shift work is significantly and positively associated with possible gastro-esophageal reflux disease: A meta-analysis study.Frontiers in public health · 2022Pooled it
- Prevalence and risk factors for gastroesophageal reflux disease in the Indian population: A meta-analysis and meta-regression study.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021Pooled it
- Prospective uncontrolled clinical study shows rapid and long lasting relief of heartburn and acid related gastric discomfort with Refluthin.Scientific reports · 2025Trial
- Efficacy of Shugan Hewei formula combined with rabeprazole in refractory gastroesophageal reflux disease: randomized, double-blind, placebo-controlled trial.European journal of medical research · 2024Trial
- Adverse events and device failures of the transoral incisionless fundoplication system: a MAUDE database analysis.Surgical endoscopy · 2026Article
- Application of High-Resolution Impedance Manometry for Evaluation of Gastroesophageal Reflux Disease in Patients with Obesity Based on the Updated Lyon Consensus 2.0 and Chicago Classification v4.0.Obesity surgery · 2026Article
- Clinical Decision-Making in Peptic Esophageal Stenosis: To PEG or Not to PEG?Clinical case reports · 2026Article
- Shared molecular signatures linking gastroesophageal reflux disease and major depressive disorder revealed by integrated machine learning.BMC gastroenterology · 2026Article
- Perceived stress, diet, and medication use associated with GERD symptoms in Lebanese adults: A cross-sectional study.Journal of public health research · 2026Article
- Article
- Effect of an alginate-based antacid and simulated gastric acid on the surface roughness and color stability of CAD/CAM resin-based materials.BMC oral health · 2026Article
- A Historical and Scientific Review of Anti-Reflux Surgery: Evolution, Evidence, and Future Directions.Current gastroenterology reports · 2026Review
- Comprehensive Assessment of Reflux Burden and Mucosal Integrity in Children: Insights from MNBI and Impedance-pH Monitoring.Children (Basel, Switzerland) · 2025Article
- Erosive Esophagitis Unveiled: A Retrospective Study of Epidemiology and Endoscopic Findings in Qassim, Saudi Arabia.Cureus · 2025Article
- Cow milk protein allergy mimics in infancy.World journal of clinical pediatrics · 2025Review
52 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastroesophageal reflux disease (GERD) is a common clinical problem, affecting millions of people worldwide. Patients are recognized by both classic and atypical symptoms. Acid suppressive therapy provides symptomatic relief and prevents complications in many individuals with GERD. Advances in diagnostic and therapeutic modalities have improved our ability to identify and manage disease complications. Here, we discuss the pathophysiology and effects of GERD, and provide information on the clinical approach to this common disorder.
Indexed as
Identifiers
30228725PMC6140167W2980777457What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.