ArticleScientific reports2018
3D multiscale imaging of human vocal folds using synchrotron X-ray microtomography in phase retrieval mode.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 35 citations in OpenAlex.
- Ethyl Cinnamate-Based Tissue Clearing Technique on Vocal Fold Mucosa with Vasculature Model.Journal of voice : official journal of the Voice Foundation · 2025Article
- A fibril-scale visco-hyperelastic model for the mechanics of vocal-fold tissues.Frontiers in bioengineering and biotechnology · 2025Article
- Optimising 4D imaging of fast-oscillating structures using X-ray microtomography with retrospective gating.Scientific reports · 2024Article
- Fourier transform-based method for quantifying the three-dimensional orientation distribution of fibrous units.Scientific reports · 2024Article
- Flow-induced oscillations of vocal-fold replicas with tuned extensibility and material properties.Scientific reports · 2023Article
- High-Resolution Phase-Contrast Tomography on Human Collagenous Tissues: A Comprehensive Review.Tomography (Ann Arbor, Mich.) · 2023Review
- Light in the Larynx: a Miniaturized Robotic Optical Fiber for In-office Laser Surgery of the Vocal Folds.Proceedings of the ... IEEE/RSJ International Conference on Intelligent Robots and Systems. IEEE/RSJ International Conference on Intelligent Robots and Systems · 2022Article
- Lower Inspiratory Breathing Depth Enhances Pulmonary Delivery Efficiency of ProAir Sprays.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Brain virtual histology with X-ray phase-contrast tomography Part I: whole-brain myelin mapping in white-matter injury models.Biomedical optics express · 2022Article
- Effect of MDI Actuation Timing on Inhalation Dosimetry in a Human Respiratory Tract Model.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Mechanics of gelatin-based hydrogels during finite strain tension, compression and shear.Frontiers in bioengineering and biotechnology · 2022Article
- On the Merits of Using Angled Fiber Tips in Office-based Laser Surgery of the Vocal Folds.Proceedings of SPIE--the International Society for Optical Engineering · 2021Article
- Quantitative evaluation of the human vocal fold extracellular matrix using multiphoton microscopy and optical coherence tomography.Scientific reports · 2021Article
- Multimodal virtual histology of rabbit vocal folds by nonlinear microscopy and nano computed tomography.Biomedical optics express · 2019Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human vocal folds possess outstanding abilities to endure large, reversible deformations and to vibrate up to more than thousand cycles per second. This unique performance mainly results from their complex specific 3D and multiscale structure, which is very difficult to investigate experimentally and still presents challenges using either confocal microscopy, MRI or X-ray microtomography in absorption mode. To circumvent these difficulties, we used high-resolution synchrotron X-ray microtomography with phase retrieval and report the first ex vivo 3D images of human vocal-fold tissues at multiple scales. Various relevant descriptors of structure were extracted from the images: geometry of vocal folds at rest or in a stretched phonatory-like position, shape and size of their layered fibrous architectures, orientation, shape and size of the muscle fibres as well as the set of collagen and elastin fibre bundles constituting these layers. The developed methodology opens a promising insight into voice biomechanics, which will allow further assessment of the micromechanics of the vocal folds and their vibratory properties. This will then provide valuable guidelines for the design of new mimetic biomaterials for the next generation of artificial larynges.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.