Evidence map›Paper›PMID 30228230›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

Neogenin in Amygdala for Neuronal Activity and Information Processing.

Xiang-Dong Sun, Wen-Bing Chen, Dong Sun, Jie Huang, Yuan-Quan Li, Jin-Xiu Pan, Ya-Nan Wang, Kai Zhao, Zhao-Qi Dong, Hong-Sheng Wang and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

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  8. Unique transsynaptic complexes enable long-term synaptic plasticity in a synapse-specific manner.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  9. Transsynaptic cerebellin 4-neogenin 1 signaling mediates LTP in the mouse dentate gyrus.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  10. Hippocampal astrocytic neogenin regulating glutamate uptake, a critical pathway for preventing epileptic response.Proceedings of the National Academy of Sciences of the United States of America · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Xiang-Dong SunSchool of Basic Medical Sciences, Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, China, doubao0512@126.com wen-cheng.xiong@case.edu.ORCID 0000-0002-0051-1463
Wen-Bing ChenDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106.
Dong SunDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106.
Jie HuangSchool of Basic Medical Sciences, Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, China.
Yuan-Quan LiSchool of Basic Medical Sciences, Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, China.
Jin-Xiu PanDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106.
Ya-Nan WangDepartment of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390.
Kai ZhaoDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106.
Zhao-Qi DongDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106.
Hong-Sheng WangDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106.
Lei XiongDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106.ORCID 0000-0002-8083-6902
Aiguo XuanSchool of Basic Medical Sciences, Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, China.
Shen-Ting ZhaoSchool of Basic Medical Sciences, Second Affiliated Hospital of Guangzhou Medical University, Guangzhou 510260, China.
Anilkumar PillaiDepartment of Psychiatry, Medical College of Georgia, Augusta University, Augusta, Georgia 30912.ORCID 0000-0002-1952-8556
Wen-Cheng XiongDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106, doubao0512@126.com wen-cheng.xiong@case.edu.
Lin MeiDepartment of Neurosciences, School of Medicine, Case Western Reserve University, Cleveland, Ohio 44106.
Augusta University · USSecond Affiliated Hospital of Guangzhou Medical University · CNNanchang University · CNThe University of Texas Southwestern Medical Center · US

Funding

Mechanisms of neuromuscular junction formationR01NS082007 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI XIONG, WEN-CHENG · 2013 to 2022
$5.2M
NRG1-ErbB4 regulation of synaptic plasticity and behaviorR01MH083317 · NIMH · CASE WESTERN RESERVE UNIVERSITY · PI MEI, LIN · 2008 to 2018
$4.3M
Characterization of Agrin/LRP4 Antibody-Positive Myasthenia GravisR01NS090083 · NINDS · CASE WESTERN RESERVE UNIVERSITY · PI MEI, LIN · 2015 to 2019
$2.9M
Retromer deficiency and Alzheimer's disease pathologyRF1AG045781 · NIA · CASE WESTERN RESERVE UNIVERSITY · PI XIONG, WEN-CHENG · 2019 to 2019
$2.0M
APP as a common denominator for Alzheimer's disease and osteoporosisR01AG051773 · NIA · CASE WESTERN RESERVE UNIVERSITY · PI XIONG, WEN-CHENG · 2016 to 2020
$2.0M
Retromer deficiency and Alzheimer's disease pathologyR01AG045781 · NIA · CASE WESTERN RESERVE UNIVERSITY · PI XIONG, WEN-CHENG · 2014 to 2017
$1.7M
Neuromuscular junction regenerationI01BX001020 · VA · LOUIS STOKES CLEVELAND VA MEDICAL CENTER · PI MEI, LIN · 2014 to 2023
–
BLRD VA I01 BX001020NIA NIH HHS R01 AG045781NIA NIH HHS R01 AG051773NIA NIH HHS RF1 AG045781NIMH NIH HHS R01 MH083317NINDS NIH HHS R01 NS082007NINDS NIH HHS R01 NS090083
6 · The paper itself

Abstract

Fear learning and memory are vital for livings to survive, dysfunctions in which have been implicated in various neuropsychiatric disorders. Appropriate neuronal activation in amygdala is critical for fear memory. However, the underlying regulatory mechanisms are not well understood. Here we report that Neogenin, a DCC (deleted in colorectal cancer) family receptor, which plays important roles in axon navigation and adult neurogenesis, is enriched in excitatory neurons in BLA (Basolateral amygdala). Fear memory is impaired in male

Indexed as

AnimalsBasolateral Nuclear ComplexExcitatory Postsynaptic PotentialsFearLearningMaleMembrane ProteinsMiceMice, TransgenicNeuronsOrgan Culture TechniquesMembrane Proteinsneogeninamygdalafear memoryNeogeninsynaptic transmission

Identifiers

PMID30228230
PMCPMC6209834
OpenAlexW2889902016

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.